Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 9/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680824 | 0.82 | SUCNR1 (0.44) | TRPV3SCN9AADORA3 | |
| SCHEMBL13680850 | 0.82 | TRPV3 (0.53) | TRPV3SCN9A | |
| SCHEMBL3854280 | 0.82 | MEN1 (0.50) | TRPV3PDE10A | |
| SCHEMBL13680834 | 0.81 | PDE10A (0.39) | TRPV3PDE10AADORA3 | |
| SCHEMBL30755516 | 0.79 | TRPV3 (0.51) | TRPV3SCN9ACTSK | |
| SCHEMBL4831269 | 0.77 | TRPV3 (0.54) | TRPV3SCN9ACHRNA7 | |
| SCHEMBL4592336 | 0.77 | TRPV3 (0.54) | TRPV3SCN9ACTSSCTSK | |
| SCHEMBL4592059 | 0.77 | TRPV3 (0.61) | TRPV3SCN9A | |
| SCHEMBL3721067 | 0.77 | TRPV3 (0.54) | TRPV3SCN9A | |
| SCHEMBL30755490 | 0.77 | TRPV3 (0.54) | TRPV3SCN9ACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |