Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680845 | 0.84 | SCN9A (0.41) | SUCNR1EPHB4TEKABL1ALDH1A1 | |
| SCHEMBL13680818 | 0.82 | TRPV3 (0.52) | ADORA3SCN9ATRPV3 | |
| SCHEMBL13680815 | 0.82 | PDE10A (0.46) | ADORA3KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL23176310 | 0.79 | SCN5A (0.48) | SUCNR1EPHB4TEKSCN5ASCN10A | |
| SCHEMBL4591287 | 0.79 | SCN5A (0.48) | SUCNR1EPHB4TEKSCN5ASCN10A | |
| SCHEMBL4590801 | 0.79 | SUCNR1 (0.48) | SUCNR1EPHB4TEKSCN5ASCN10A | |
| SCHEMBL13680840 | 0.79 | RAB9A (0.41) | NPC1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL3854280 | 0.78 | MEN1 (0.50) | ALDH1A1RAB9ATRPV3 | |
| SCHEMBL13680838 | 0.78 | SCN9A (0.42) | NPC1MAPTRAB9ASCN9A | |
| SCHEMBL13680823 | 0.77 | TRPV3 (0.34) | TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |