Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 9/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680846 | 0.82 | MAPT (0.40) | TRPV3SCN9A | |
| SCHEMBL13680818 | 0.82 | TRPV3 (0.52) | TRPV3SCN9A | |
| SCHEMBL13680845 | 0.81 | SCN9A (0.41) | TRPV3SCN9A | |
| SCHEMBL27362246 | 0.81 | TRPV3 (0.63) | TRPV3SCN9A | |
| SCHEMBL13680847 | 0.80 | PDE10A (0.43) | TRPV3SCN9AKCNH2 | |
| SCHEMBL8648745 | 0.78 | P2RX7 (0.41) | KCNH2 | |
| SCHEMBL13680848 | 0.77 | ADK (0.40) | SCN9AKCNH2 | |
| SCHEMBL13680952 | 0.77 | CPT1A (0.41) | — | |
| SCHEMBL13680849 | 0.76 | SCN9A (0.43) | SCN9A | |
| SCHEMBL13680824 | 0.76 | SUCNR1 (0.44) | TRPV3SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |