Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 5/20 | 0.39 |
| ▸ | CDK8 | P49336 | 5/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 5/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | TCF7 | P36402 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680984 | 0.76 | LMNA (0.39) | APPTRPA1CCNCCDK8FAAH | |
| SCHEMBL13680459 | 0.76 | APP (0.49) | APPTRPA1CCNCCDK8FAAH | |
| SCHEMBL13680855 | 0.75 | IRAK4 (0.42) | TRPA1CCNCCDK8ARBRD4 | |
| SCHEMBL13680866 | 0.71 | ALDH1A1 (0.60) | — | |
| SCHEMBL13680899 | 0.71 | CYP2C19 (0.40) | — | |
| SCHEMBL13681006 | 0.71 | CYP2C19 (0.39) | — | |
| SCHEMBL13681030 | 0.70 | ALDH1A1 (0.37) | BRD4CREBBP | |
| SCHEMBL13681027 | 0.70 | HTR6 (0.32) | — | |
| SCHEMBL13681328 | 0.70 | CREBBP (0.40) | APPTRPA1CCNCCDK8FAAH | |
| SCHEMBL13680974 | 0.70 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |