Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.38 |
| ▸ | CPT1A | P50416 | 1/20 | 0.38 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681049 | 0.85 | LMNA (0.38) | GAAKDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL13680954 | 0.84 | KDM4E (0.40) | GAAKDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL13680953 | 0.84 | LMNA (0.41) | GAAKDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13680959 | 0.83 | CYP19A1 (0.53) | GAAKDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL13680926 | 0.83 | LMNA (0.56) | KDM4ELMNASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL13680952 | 0.81 | CPT1A (0.41) | KDM4ELMNASMN1; SMN2CPT1AMAPT | |
| SCHEMBL13680949 | 0.81 | HPGDS (0.43) | GAAKDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13681331 | 0.81 | CHEK1 (0.41) | GAAKDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL7039927 | 0.80 | KDM4E (0.60) | GAAKDM4ELMNASMN1; SMN2RAB9A | |
| SCHEMBL13681042 | 0.80 | RAB9A (0.36) | GAAKDM4ELMNASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |