Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CPT2 | P23786 | 1/20 | 0.41 |
| ▸ | CPT1A | P50416 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680950 | 0.86 | PPARD (0.40) | CYP19A1KDM4EALDH1A1HPGDRAB9A | |
| SCHEMBL13680956 | 0.84 | SHMT2 (0.40) | CYP19A1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL13680955 | 0.83 | GAA (0.42) | CYP2A6KDM4EALDH1A1HPGDCPT2 | |
| SCHEMBL13680989 | 0.83 | KDM4E (0.39) | CYP19A1KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL13680929 | 0.82 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDTDP1RAB9A | |
| SCHEMBL13680954 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1RAB9AGAAMAPT | |
| SCHEMBL13680953 | 0.81 | LMNA (0.41) | CYP2A6KDM4EALDH1A1HPGDGAA | |
| SCHEMBL28731211 | 0.80 | CYP19A1 (0.56) | CYP19A1CYP2A6KDM4EALDH1A1HPGD | |
| SCHEMBL13681049 | 0.79 | LMNA (0.38) | KDM4EALDH1A1HPGDRAB9AGAA | |
| SCHEMBL5469319 | 0.79 | KDM4E (0.68) | CYP19A1CYP2A6KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |