Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680937 | 0.82 | KDM4E (0.52) | LMNAALDH1A1TP53MAPTKDM4E | |
| SCHEMBL13680953 | 0.81 | LMNA (0.41) | PRMT1LMNAALDH1A1TP53MAPT | |
| SCHEMBL13680955 | 0.81 | GAA (0.42) | PRMT1LMNAALDH1A1TP53MAPT | |
| SCHEMBL13680950 | 0.79 | PPARD (0.40) | LMNAALDH1A1TP53MAPTKDM4E | |
| SCHEMBL13680954 | 0.79 | KDM4E (0.40) | PRMT1LMNAALDH1A1TP53MAPT | |
| SCHEMBL13680959 | 0.78 | CYP19A1 (0.53) | LMNAALDH1A1TP53MAPTKDM4E | |
| SCHEMBL13681331 | 0.78 | CHEK1 (0.41) | LMNAALDH1A1TP53MAPTKDM4E | |
| SCHEMBL13680952 | 0.78 | CPT1A (0.41) | LMNATP53MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL13680943 | 0.77 | RAB9A (0.48) | LMNAALDH1A1TP53MAPTKDM4E | |
| SCHEMBL13681052 | 0.77 | HPGDS (0.54) | HPGDSLMNATP53MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |