Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | EIF4E | P06730 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13681049 | 0.85 | LMNA (0.38) | KDM4EALDH1A1HPGDRAB9AGAA | |
| SCHEMBL13680959 | 0.83 | CYP19A1 (0.53) | KDM4EALDH1A1HPGDTDP1RAB9A | |
| SCHEMBL13681042 | 0.82 | RAB9A (0.36) | KDM4EALDH1A1RAB9AGAAMAPT | |
| SCHEMBL13681046 | 0.81 | RAB9A (0.35) | KDM4EALDH1A1HPGDRAB9AGAA | |
| SCHEMBL13681035 | 0.81 | LMNA (0.38) | KDM4EALDH1A1HPGDRAB9AGAA | |
| SCHEMBL13681058 | 0.80 | MAPT (0.37) | KDM4EALDH1A1HPGDGAAMAPT | |
| SCHEMBL13681036 | 0.80 | KMT2A (0.37) | KDM4EALDH1A1HPGDRAB9AGAA | |
| SCHEMBL13680929 | 0.80 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDTDP1RAB9A | |
| SCHEMBL13681312 | 0.80 | LMNA (0.33) | KDM4EALDH1A1HPGDRAB9AGAA | |
| SCHEMBL13680955 | 0.78 | GAA (0.42) | KDM4EALDH1A1HPGDRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |