Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 7/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13680957 | 0.84 | KDM4E (0.50) | ALDH1A1KDM4ERAB9ATDP1HPGD | |
| SCHEMBL13680926 | 0.84 | LMNA (0.56) | ALDH1A1KDM4ERAB9AMAPTLMNA | |
| SCHEMBL13680931 | 0.83 | SHMT2 (0.56) | ALDH1A1KDM4ERAB9ATDP1HPGD | |
| SCHEMBL13680958 | 0.82 | RXFP1 (0.57) | ALDH1A1KDM4ERAB9AHPGDMAPT | |
| SCHEMBL13680959 | 0.82 | CYP19A1 (0.53) | ALDH1A1KDM4ERAB9ATDP1HPGD | |
| SCHEMBL13680942 | 0.82 | KDM4E (0.47) | ALDH1A1KDM4ERAB9ATDP1HPGD | |
| SCHEMBL13680941 | 0.81 | KDM4E (0.47) | ALDH1A1KDM4ERAB9ATDP1HPGD | |
| SCHEMBL13680939 | 0.81 | MAPT (0.47) | ALDH1A1KDM4ERAB9ATDP1HPGD | |
| SCHEMBL13680922 | 0.81 | GFER (0.62) | ALDH1A1KDM4ERAB9AMAPTLMNA | |
| SCHEMBL2072430 | 0.81 | KDM4E (0.67) | ALDH1A1KDM4ERAB9ATDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |