Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13691855 | 0.90 | DRD2 (0.45) | DRD2DRD3KMT2AHTR1ACACNA1G | |
| SCHEMBL13691857 | 0.89 | DRD2 (0.45) | DRD2DRD3KMT2AHTR1ACCR1 | |
| SCHEMBL13691859 | 0.88 | OPRK1 (0.43) | DRD2DRD3RAB9ANPC1HTR1A | |
| SCHEMBL13189113 | 0.86 | UTS2R (0.38) | DRD2DRD3KMT2ARAB9ANPC1 | |
| SCHEMBL13189116 | 0.85 | UTS2R (0.39) | DRD2DRD3KMT2ANPC1HTR1A | |
| SCHEMBL13689546 | 0.82 | DRD2 (0.44) | DRD2DRD3KMT2AHTR1ACACNA1G | |
| SCHEMBL13188483 | 0.82 | DRD2 (0.44) | DRD2DRD3KMT2AHTR1ACACNA1G | |
| SCHEMBL19474295 | 0.82 | DRD2 (0.44) | DRD2DRD3KMT2AHTR1ACACNA1G | |
| SCHEMBL13691779 | 0.82 | DRD2 (0.44) | DRD2DRD3KMT2AHTR1ACACNA1G | |
| SCHEMBL13691778 | 0.82 | DRD2 (0.44) | DRD2DRD3KMT2AHTR1ACACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096854-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC3 AND/OR MC4 RECEPTORS AND TREATMENT OF CONDITIONS RELATED TO THESE RECEPTORS | MIMETICA PTY LTD (AU) | 2010-09-02 | — | — | WO | disclosed |