Sugi Predict

Sugi Predict / Compounds / SCHEMBL1369665

SCHEMBL1369665

SCHEMBL1369665

OB(O)c1cccc(-c2cccnc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 1/20 0.60
▸ CYP2A6 P11509 3/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ CYP1A2 P05177 1/20 0.56
▸ CYP3A4 P08684 1/20 0.56
▸ MKNK1 Q9BUB5 4/20 0.55
▸ MKNK2 Q9HBH9 4/20 0.55
▸ MEN1 O00255 1/20 0.55
▸ PSIP1 O75475 1/20 0.55
▸ AXL P30530 1/20 0.55
▸ KMO O15229 1/20 0.53
▸ PLG P00747 1/20 0.49
▸ F12 P00748 1/20 0.49
▸ F11 P03951 1/20 0.49
▸ KLKB1 P03952 1/20 0.49
▸ PRSS1 P07477 1/20 0.49
▸ PRSS2 P07478 1/20 0.49
▸ PRSS3 P35030 1/20 0.49
▸ ERN1 O75460 1/20 0.49
▸ CYP11B1 P15538 5/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12129633 0.96 MGLL (0.56) MGLLCYP2A6ALDH1A1CYP1A2CYP3A4
SCHEMBL29419989 0.87 CYP2A6 (0.58) CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1
SCHEMBL2479963 0.87 CYP2A6 (0.58) CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1
SCHEMBL17005614 0.85 KMO (0.51) MGLLCYP2A6ALDH1A1CYP1A2CYP3A4
SCHEMBL10028689 0.85 CYP2A6 (0.56) CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1
SCHEMBL29958045 0.85 CYP2A6 (0.56) CYP2A6ALDH1A1CYP1A2CYP3A4MKNK1
SCHEMBL23406919 0.83 MGLL (0.58) MGLLCYP2A6ALDH1A1CYP1A2CYP3A4
SCHEMBL31184131 0.83 MGLL (0.58) MGLLCYP2A6ALDH1A1CYP1A2CYP3A4
SCHEMBL28926466 0.83 MGLL (0.54) MGLLCYP2A6ALDH1A1CYP1A2CYP3A4
SCHEMBL17005610 0.83 MGLL (0.50) MGLLCYP2A6ALDH1A1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114249685-A Ortho-diaryl substituted phenanthrene or phenanthroline carrier transport material and preparation method and application thereof 华南理工大学 2022-03-29 — — CN claimed
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2025-06-12 — — US disclosed
US-12317744-B2 Compound having a fused-azole ring structure and organic electroluminescent element HODOGAYA CHEMICAL CO., LTD. (JP) 2025-05-27 — — US disclosed
US-20240400555-A1 Compounds, Compositions and Methods for Attenuation of Mammalian Translation of C-MYC or N-MYC Proteins of the MYC Proto-Oncogene Family of BHLH Transcription Factors INITIAL THERAPEUTICS, INC. (US) 2024-12-05 — — US disclosed
WO-2024226875-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR ATTENUATION OF MAMMALIAN TRANSLATION OF C-MYC OR N-MYC PROTEINS OF THE MYC PROTO-ONCOGENE FAMILY OF BHLH TRANSCRIPTION FACTORS INITIAL THERAPEUTICS, INC. (US) 2024-10-31 — — WO disclosed
CN-112805845-B Compound having azabenzoxazole ring structure and organic electroluminescent element 保土谷化学工业株式会社 2024-10-25 — — CN disclosed
EP-4447963-A1 SELECTIVE PHD1 INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE Akebia Therapeutics Inc. (US) 2024-10-23 — — EP disclosed
US-20240336568-A1 SELECTIVE PHD1 INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE AKEBIA THERAPEUTICS, INC. (US) 2024-10-10 — — US disclosed
CN-118715015-A Selective PHD1 inhibitor compounds, compositions and methods of use 阿克比治疗有限公司 2024-09-27 — — CN disclosed
US-20240228470-A1 Organic Compound And Organic Light Emitting Device Including Same P&H TECH CO., LTD (KR) 2024-07-11 — — US disclosed
US-8674091-B2 1,3,5-triazine derivative, process for producing same, and organic electroluminescent element comprising same as constituent TOSOH CORPORATION (JP) 2014-03-18 — — US disclosed
US-20120214993-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT SAGAMI CHEMICAL RESEARCH INSTITUTE, (JP) 2012-08-23 — — US disclosed
US-20120214993-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT SAGAMI CHEMICAL RESEARCH INSTITUTE, (JP) 2012-08-23 — — US disclosed
US-20120214993-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT SAGAMI CHEMICAL RESEARCH INSTITUTE, (JP) 2012-08-23 — — US disclosed
EP-2468731-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT Tosoh Corporation (JP) 2012-06-27 — — EP disclosed
US-20110288295-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) 2011-11-24 — — US disclosed
US-20110288295-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) 2011-11-24 — — US disclosed
US-20110288295-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) 2011-11-24 — — US disclosed
EP-2361909-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME Tosoh Corporation (JP) 2011-08-31 — — EP disclosed
EP-2361909-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME Tosoh Corporation (JP) 2011-08-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION KMT5A, KMT5B, KMT5C MGLL 4097/4885CYP2A6 1341/4885ALDH1A1 2233/4885
US-20110288295-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME VDAC1, MT-ND5, TRPC5 MGLL 4044/4885CYP2A6 2901/4885ALDH1A1 235/4885
US-12317744-B2 Compound having a fused-azole ring structure and organic electroluminescent element SLC19A1, LEF1, SLCO4C1 MGLL 4355/4885CYP2A6 2750/4885ALDH1A1 843/4885
US-20240400555-A1 Compounds, Compositions and Methods for Attenuation of Mammalian Translation of C-MYC or N-MYC Proteins of the MYC Proto-Oncogene Family of BHLH Transcription Factors MYCBP, MYC, MYCBP2 MGLL 3867/4885CYP2A6 3954/4885ALDH1A1 3684/4885
US-20240228470-A1 Organic Compound And Organic Light Emitting Device Including Same OR10J3, ORMDL3, OR51E2 MGLL 403/4885CYP2A6 1839/4885ALDH1A1 249/4885
US-20120214993-A1 CYCLIC AZINE DERIVATIVES, PROCESSES FOR PRODUCING THESE, AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THESE AS COMPONENT CPNE4, EPB41, AZI2 MGLL 3377/4885CYP2A6 3586/4885ALDH1A1 267/4885
US-20240336568-A1 SELECTIVE PHD1 INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE HIF1AN, EGLN1, EGLN2 MGLL 4285/4885CYP2A6 2266/4885ALDH1A1 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.