Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 6/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2936513 | 0.83 | PDE4B (0.41) | PDE4BTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2935943 | 0.80 | PKM (0.51) | PDE4BHSD17B10PDE4APDE4CPDE4D | |
| SCHEMBL2938117 | 0.72 | TUBB4A (0.42) | PDE4BTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL535644 | 0.71 | GABRP (0.39) | PDE4BHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL13697644 | 0.69 | NT5E (0.38) | PDE4BHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL13697639 | 0.69 | NT5E (0.38) | HSD17B10KDM4EALDH1A1HPGDNT5E | |
| SCHEMBL535729 | 0.68 | IGF1R (0.39) | PDE4BALDH1A1POLBSORT1IGF1R | |
| SCHEMBL3541953 | 0.68 | POLB (0.60) | PDE4BTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30640906 | 0.68 | POLB (0.60) | PDE4BTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28226031 | 0.68 | TAS2R14 (0.51) | PDE4BKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221587-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221587-A1 | NOVEL INSECTICIDES | DDT, CYP4F11, ACHE | PDE4B 1031/4885TUBB4A 365/4885TUBB 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.