Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAOA | P21397 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19009222 | 0.89 | MAOA (0.68) | ALDH1A1MAOAMAOBACHENPY5R | |
| SCHEMBL2721051 | 0.86 | MAOA (0.59) | ALDH1A1MAOAMAOBACHEHPGD | |
| SCHEMBL17517483 | 0.85 | MAOA (0.67) | MAOAMAOBACHEKDM4EMEN1 | |
| SCHEMBL17517482 | 0.85 | CYP1A2 (0.65) | MAOAMAOBACHEKDM4EIDO1 | |
| SCHEMBL2216201 | 0.83 | MAOA (0.65) | ALDH1A1MAOAMAOBACHEHPGD | |
| SCHEMBL29360167 | 0.82 | ALDH1A1 (0.75) | ALDH1A1HPGDMAPK1HTTKDM4E | |
| SCHEMBL29963695 | 0.82 | ALDH1A1 (0.75) | ALDH1A1HPGDMAPK1HTTKDM4E | |
| SCHEMBL151563 | 0.82 | ALDH1A1 (0.75) | ALDH1A1HPGDMAPK1HTTKDM4E | |
| SCHEMBL19271271 | 0.82 | NPY5R (0.50) | ALDH1A1NPY5RHPGDMAPK1HTT | |
| SCHEMBL17102952 | 0.82 | MAOA (0.68) | ALDH1A1MAOAMAOBACHEHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542260-B2 | Composition of matter for use in organic light-emitting diodes | KYULUX, INC. (JP) | 2023-01-03 | — | — | US | disclosed |
| US-20210066613-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | KYULUX, INC. (JP) | 2021-03-04 | — | — | US | disclosed |
| US-20200203622-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | KYULUX, INC. (JP) | 2020-06-25 | — | — | US | disclosed |
| US-10644249-B2 | Composition of matter for use in organic light-emitting diodes | KYULUX, INC. (JP) | 2020-05-05 | — | — | US | disclosed |
| US-20190267554-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | Kyulux North America, Inc. | 2019-08-29 | — | — | US | disclosed |
| US-20190233412-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | Kyulux North America, Inc. | 2019-08-01 | — | — | US | disclosed |
| US-20170244043-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-08-24 | — | — | US | disclosed |
| US-20170174705-A1 | CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-06-22 | — | — | US | disclosed |
| US-9107914-B2 | Beta-carbolines for use in the treatment of hearing loss and vertigo | AUDIOCURE PHARMA GMBH (DE) | 2015-08-18 | — | — | US | disclosed |
| US-9107914-B2 | Beta-carbolines for use in the treatment of hearing loss and vertigo | AUDIOCURE PHARMA GMBH (DE) | 2015-08-18 | — | — | US | disclosed |
| WO-2012059232-A1 | CARBAZOLE AND CARBOLINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC APPLICATIONS THEREOF | PHILIP MORRIS PRODUCTS S.A (CH) | 2012-05-10 | — | — | WO | disclosed |
| EP-1634881-B1 | HARMINE DERIVATIVES, INTERMEDIATES USED IN THEIR PREPARATION, PREPARATION PROCESSES AND USE THEREOF | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD (CN) | 2011-07-27 | — | — | EP | disclosed |
| WO-2011079841-A1 | BETA-CARBOLINES FOR USE IN THE TREATMENT OF HEARING LOSS AND VERTIGO | ROMMELSPACHER HANS (DE) | 2011-07-07 | — | — | WO | disclosed |
| US-20100143474-A1 | B-CARBOLINE FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | ELLNEUROXX, LTD. | 2010-06-10 | — | — | US | disclosed |
| US-20100143474-A1 | B-CARBOLINE FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | ELLNEUROXX, LTD. | 2010-06-10 | — | — | US | disclosed |
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | XINJIANG HUASHIDAN PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2009-09-10 | — | — | US | disclosed |
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | XINJIANG HUASHIDAN PHARMACEUTICAL RESEARCH CO., LTD. (CN) | 2009-09-10 | — | — | US | disclosed |
| WO-2008104161-A1 | ß-CARBOLINES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | ELLNEUROXX LTD. (DE) | 2008-09-04 | — | — | WO | disclosed |
| US-20070009760-A1 | Coordination metal compound, material for organic electroluminescence device, material for luminescent coating formation and organic electroluminescence device | INOUE TETSUYA | 2007-01-11 | — | — | US | disclosed |
| EP-1634881-A1 | HARMINE DERIVATIVES, INTERMEDIATES USED IN THEIR PREPARATION, PREPARATION PROCESSES AND USE THEREOF | Xinjiang Huashidan Pharmaceutical Research Co., Ltd. (CN) | 2006-03-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174705-A1 | CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE CONDENSED CYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND, AND METHOD OF MANUFACTURING THE ORGANIC LIGHT-EMITTING DEVICE | CRY1, C9, CRY2 | ALDH1A1 490/4885MAOA 2923/4885MAOB 2742/4885 |
| US-11542260-B2 | Composition of matter for use in organic light-emitting diodes | CRY2, NDUFV3, SLCO1B3 | ALDH1A1 254/4885MAOA 164/4885MAOB 108/4885 |
| US-20190233412-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | CRY2, NDUFV3, SLCO1B3 | ALDH1A1 254/4885MAOA 164/4885MAOB 108/4885 |
| US-20100143474-A1 | B-CARBOLINE FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | PARK7, SNCA, CHAT | ALDH1A1 203/4885MAOA 130/4885MAOB 48/4885 |
| US-10644249-B2 | Composition of matter for use in organic light-emitting diodes | NDUFV3, SLCO1B3, CRY2 | ALDH1A1 99/4885MAOA 120/4885MAOB 75/4885 |
| US-20090227619-A1 | Harmine derivatives, intermediates used in their preparations, preparation processes and use therefo | TPH1, HTR1F, TPH2 | ALDH1A1 324/4885MAOA 48/4885MAOB 16/4885 |
| US-20200203622-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | NDUFV3, NDUFV2, CRY2 | ALDH1A1 96/4885MAOA 120/4885MAOB 54/4885 |
| US-20190267554-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | NDUFV3, SLCO1B3, CRY2 | ALDH1A1 99/4885MAOA 120/4885MAOB 75/4885 |
| US-20210066613-A1 | COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES | CRY2, CYBA, NDUFV3 | ALDH1A1 116/4885MAOA 169/4885MAOB 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.