Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13701752 | 0.86 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2LMNABRAF | |
| SCHEMBL13702396 | 0.77 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2BRAFSMN1; SMN2 | |
| SCHEMBL31082091 | 0.77 | TAS1R3 (0.55) | TAS1R3TAS1R1TAS1R2BRAFSMN1; SMN2 | |
| SCHEMBL15962773 | 0.75 | TAS1R3 (0.57) | TAS1R3TAS1R1TAS1R2LMNABRAF | |
| SCHEMBL28443247 | 0.75 | NPC1 (0.58) | LMNAMRGPRX4SMN1; SMN2HTTNPC1 | |
| SCHEMBL2997667 | 0.74 | KDM4E (0.55) | TAS1R3TAS1R1TAS1R2LMNABRAF | |
| SCHEMBL1742088 | 0.74 | EGLN1 (0.50) | EGLN1EGLN3NPC1RAB9AMEN1 | |
| SCHEMBL13875969 | 0.74 | TAS1R3 (0.44) | TAS1R3TAS1R1TAS1R2EGLN1EGLN3 | |
| SCHEMBL13702150 | 0.73 | FDPS (0.57) | TAS1R3TAS1R1TAS1R2LMNABRAF | |
| SCHEMBL13702293 | 0.73 | TAS1R3 (0.51) | TAS1R3TAS1R1TAS1R2LMNABRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110319396-A1 | BENZODIAZEPIN-2-ON DERIVATIVES | MSD K.K. (JP) | 2011-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319396-A1 | BENZODIAZEPIN-2-ON DERIVATIVES | DGAT1, DGAT2, GRIN1 | TAS1R3 2146/4885TAS1R1 1196/4885TAS1R2 1331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.