Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA3 | P07451 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA6 | P23280 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6743343 | 0.90 | CA12 (0.61) | CA12CA2CA3CA4CA6 | |
| Hydrochloric Acid SCHEMBL8310418 | 0.90 | CA12 (0.61) | CA12CA2CA3CA4CA6 | |
| Hydrochloric Acid SCHEMBL2829185 | 0.90 | CA12 (0.61) | CA12CA2CA3CA4CA6 | |
| Hydrochloric Acid SCHEMBL4527188 | 0.90 | CA12 (0.61) | CA12CA2CA3CA4CA6 | |
| Hydrochloric Acid SCHEMBL10631334 | 0.90 | CA12 (0.61) | CA12CA2CA3CA4CA6 | |
| Hydrochloric Acid SCHEMBL27676803 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL28720129 | 0.90 | CA12 (0.61) | CA12CA2CA3CA4CA6 | |
| Hydrochloric Acid SCHEMBL28208260 | 0.90 | CA12 (0.61) | CA12CA2CA3CA4CA6 | |
| SCHEMBL10425918 | 0.89 | CA12 (0.73) | CA12CA2CA3CA4CA6 | |
| SCHEMBL4658729 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420424-B | Synthesis method of diaryl sulfoxide derivative | 夏禾科技(江苏)有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-118420424-A | Synthesis method of diaryl sulfoxide derivative | 夏禾科技(江苏)有限公司 | 2024-08-02 | — | — | CN | claimed |
| CN-118420424-B | Synthesis method of diaryl sulfoxide derivative | 夏禾科技(江苏)有限公司 | 2024-12-27 | — | — | CN | disclosed |
| CN-118420424-A | Synthesis method of diaryl sulfoxide derivative | 夏禾科技(江苏)有限公司 | 2024-08-02 | — | — | CN | disclosed |
| CN-116874416-A | Preparation method of 4-iodo-3-methoxypyridine | 南京合巨药业有限公司 | 2023-10-13 | — | — | CN | disclosed |
| EP-3555095-B1 | INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2023-04-12 | — | — | EP | disclosed |
| US-11342511-B2 | Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same | SK MATERIALS JNC CO., LTD. (KR) | 2022-05-24 | — | — | US | disclosed |
| CN-107531641-B | Material for transporting electrons, organic electroluminescent element, and display device or lighting device | 爱思开新材料捷恩智株式会社 | 2022-03-15 | — | — | CN | disclosed |
| CN-107501023-B | Method for preparing halogenated (hetero) arene | 辽宁大学 | 2020-08-25 | — | — | CN | disclosed |
| CN-107266481-B | Material for organic electroluminescent element, display device, and lighting device | 捷恩智株式会社 | 2020-04-14 | — | — | CN | disclosed |
| US-20190214575-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE | JNC CORPORATION (JP) | 2019-07-11 | — | — | US | disclosed |
| US-20100185019-A1 | CATALYST COMPOSITION AND PROCESS FOR PRODUCING CROSS-COUPLED COMPOUND USING SAME | TOSOH FINECHEM CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| EP-2168680-A1 | CATALYST COMPOSITION AND METHOD FOR PRODUCING CROSS-COUPLING COMPOUND USING THE SAME | Kyoto University (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-7569694-B2 | Coumarin compound, material for light emitting device and organic electroluminescent device | CHISSO CORPORATION (JP) | 2009-08-04 | — | — | US | disclosed |
| US-20090134780-A1 | Electron transport material and organic electroluminescent device using the same | SK MATERIALS JNC CO., LTD. (KR) | 2009-05-28 | — | — | US | disclosed |
| US-20070176544-A1 | Coumarin compound, material for light emitting device and organic electroluminescent device | JNC CORPORATION (JP) | 2007-08-02 | — | — | US | disclosed |
| US-20040024216-A1 | HMG-CoA reductase inhibitors and method | ROBL JEFFREY A (US) | 2004-02-05 | — | — | US | disclosed |
| US-6620821-B2 | Tricyclic imine or amine oxime derivative; may be used in combination with one or more hypolipidemic agents or lipid-lowering agents or lipid agents or lipid modulating agents, and/or one or more other types of therapeutic agents | BRISTOL-MYERS SQUIBB COMPANY | 2003-09-16 | — | — | US | disclosed |
| US-20020061901-A1 | HMG-CoA reductase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY | 2002-05-23 | — | — | US | disclosed |
| US-20020028826-A1 | HMG-CoA reductase inhibitors and method | BRISTOL-MYERS SQUIBB COMPANY | 2002-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061901-A1 | HMG-CoA reductase inhibitors and method | HMGCR, LDLR, NR1H2 | CHRM2 1411/4885CHRM1 1487/4885CHRM3 1540/4885 |
| US-11342511-B2 | Azoline ring-containing compound, electron transport/injection layer material containing the same, and organic electroluminescent element using the same | SLC7A5, EML4, ARNT | CHRM2 912/4885CHRM1 344/4885CHRM3 683/4885 |
| US-20020028826-A1 | HMG-CoA reductase inhibitors and method | HMGCR, LDLR, NR1H2 | CHRM2 1494/4885CHRM1 1544/4885CHRM3 1618/4885 |
| US-20190214575-A1 | MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE | L1CAM, VDAC1, VDAC2 | CHRM2 396/4885CHRM1 228/4885CHRM3 713/4885 |
| US-20040024216-A1 | HMG-CoA reductase inhibitors and method | HMGCR, LDLR, NR1H2 | CHRM2 1381/4885CHRM1 1505/4885CHRM3 1697/4885 |
| US-20090134780-A1 | Electron transport material and organic electroluminescent device using the same | SLC25A11, ELAVL1, SLC26A3 | CHRM2 1490/4885CHRM1 1115/4885CHRM3 1750/4885 |
| US-20070176544-A1 | Coumarin compound, material for light emitting device and organic electroluminescent device | TRPA1, CYP3A4, UGT1A10 | CHRM2 1193/4885CHRM1 617/4885CHRM3 577/4885 |
| US-20100185019-A1 | CATALYST COMPOSITION AND PROCESS FOR PRODUCING CROSS-COUPLED COMPOUND USING SAME | PYM1, CHRM2, CHRM1 | CHRM2 2/4885CHRM1 3/4885CHRM3 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.