Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DCK | P27707 | 4/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
| ▸ | POLG | P54098 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16131607 | 0.91 | ALDH1A1 (0.38) | ALDH1A1HTTDCKALBPOLG | |
| SCHEMBL13708357 | 0.82 | ALDH1A1 (0.37) | ALDH1A1HTTDCKALBPOLG | |
| SCHEMBL6285023 | 0.78 | DCK (0.44) | ALDH1A1HTTDCKALBPOLG | |
| SCHEMBL12702728 | 0.78 | DCK (0.39) | ALDH1A1HTTDCKALBPOLG | |
| SCHEMBL16131588 | 0.78 | ST6GAL1 (0.40) | ALDH1A1HTTLMNANT5E | |
| SCHEMBL7165048 | 0.77 | ALDH1A1 (0.36) | ALDH1A1HTTDCKALBPOLG | |
| SCHEMBL11598911 | 0.76 | MEN1 (0.55) | ALDH1A1HTTDCKALBLMNA | |
| SCHEMBL12724467 | 0.74 | ALB (0.49) | ALDH1A1HTTDCKALBPRMT5 | |
| SCHEMBL12702729 | 0.74 | ALB (0.49) | ALDH1A1HTTDCKALBPRMT5 | |
| SCHEMBL16131594 | 0.74 | ALB (0.49) | ALDH1A1HTTDCKALBPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115927-A2 | NUCLEOTIDE ANALOGUES WITH QUATERNARY CARBON STEREOGENIC CENTERS AND METHODS OF USE | INSTITUT DE RECHERCHES CLINIQUES DE MONTREAL (CA) | 2009-09-24 | — | — | WO | disclosed |