Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DCK | P27707 | 5/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | POLG | P54098 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13708355 | 0.91 | ALDH1A1 (0.42) | ALDH1A1HTTDCKALBPOLG | |
| SCHEMBL16131588 | 0.87 | ST6GAL1 (0.40) | ALDH1A1HTTMEN1USP2POLB | |
| SCHEMBL13708357 | 0.86 | ALDH1A1 (0.37) | ALDH1A1HTTDCKALBMEN1 | |
| SCHEMBL12702728 | 0.85 | DCK (0.39) | ALDH1A1HTTDCKALBPOLB | |
| SCHEMBL7165048 | 0.82 | ALDH1A1 (0.36) | ALDH1A1HTTDCKALBMEN1 | |
| SCHEMBL11598911 | 0.78 | MEN1 (0.55) | ALDH1A1HTTDCKALBMEN1 | |
| SCHEMBL21714530 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HTTDCKALBMEN1 | |
| SCHEMBL21714532 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HTTDCKALBMEN1 | |
| SCHEMBL12473638 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HTTDCKALBMEN1 | |
| SCHEMBL16131585 | 0.76 | ALDH1A1 (0.36) | ALDH1A1HTTMEN1USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846636-B2 | Nucleoside analogues with quaternary carbon stereogenic centers and methods of use | LCB PHARMA INC. (CA) | 2014-09-30 | — | — | US | disclosed |