Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | DCK | P27707 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | POLG | P54098 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16131607 | 0.86 | ALDH1A1 (0.38) | ALDH1A1DCKHTTALBPOLB | |
| SCHEMBL13708355 | 0.82 | ALDH1A1 (0.42) | ALDH1A1DCKHTTALBPOLG | |
| SCHEMBL7165048 | 0.81 | ALDH1A1 (0.36) | ALDH1A1DCKHTTALBPOLB | |
| SCHEMBL11598911 | 0.78 | MEN1 (0.55) | ALDH1A1DCKHTTALBPOLB | |
| SCHEMBL12473638 | 0.78 | ALDH1A1 (0.41) | ALDH1A1DCKHTTALBPOLB | |
| SCHEMBL21714530 | 0.78 | ALDH1A1 (0.41) | ALDH1A1DCKHTTALBPOLB | |
| SCHEMBL21714532 | 0.78 | ALDH1A1 (0.41) | ALDH1A1DCKHTTALBPOLB | |
| SCHEMBL13708360 | 0.78 | NT5E (0.40) | ALDH1A1MAPT | |
| SCHEMBL12702728 | 0.76 | DCK (0.39) | ALDH1A1DCKHTTALBPOLB | |
| SCHEMBL13708356 | 0.75 | MEN1 (0.35) | ALDH1A1HTTPOLBMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009115927-A2 | NUCLEOTIDE ANALOGUES WITH QUATERNARY CARBON STEREOGENIC CENTERS AND METHODS OF USE | INSTITUT DE RECHERCHES CLINIQUES DE MONTREAL (CA) | 2009-09-24 | — | — | WO | disclosed |