Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP4 | P49662 | 1/20 | 0.41 |
| ▸ | CASP5 | P51878 | 1/20 | 0.41 |
| ▸ | CASP9 | P55211 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.41 |
| ▸ | GLP1R | P43220 | 5/20 | 0.40 |
| ▸ | RXFP4 | Q8TDU9 | 3/20 | 0.40 |
| ▸ | RXFP3 | Q9NSD7 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13724714 | 0.97 | CASP1 (0.43) | CASP1CASP3CASP4CASP5CASP9 | |
| SCHEMBL13724586 | 0.96 | CASP1 (0.42) | CASP1CASP3CASP4CASP5CASP9 | |
| SCHEMBL13724465 | 0.95 | CASP1 (0.45) | CASP1CASP3CASP4CASP5CASP9 | |
| SCHEMBL13723798 | 0.94 | OPRM1 (0.46) | GLP1RRXFP4RXFP3OPRM1OPRD1 | |
| SCHEMBL13722817 | 0.93 | VIPR1 (0.44) | GLP1RCTSBCTSK | |
| SCHEMBL13724408 | 0.93 | CASP1 (0.41) | CASP1CASP3CASP4CASP5CASP9 | |
| SCHEMBL13724669 | 0.93 | CASP1 (0.41) | CASP1CASP3CASP4CASP5CASP9 | |
| SCHEMBL14404794 | 0.93 | CASP1 (0.41) | CASP1CASP3CASP4CASP5CASP9 | |
| SCHEMBL13723911 | 0.92 | CTSB (0.45) | GLP1RRXFP4RXFP3OPRM1OPRD1 | |
| SCHEMBL13723237 | 0.92 | CTSB (0.46) | GLP1RRXFP4RXFP3OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076285-B2 | Lysobactin amides | AICURIS GMBH & CO. KG (DE) | 2011-12-13 | — | — | US | disclosed |
| US-20090203582-A1 | LYSOBACTIN AMIDES | BAYER HEALTHCARE AG (DE) | 2009-08-13 | — | — | US | disclosed |
| WO-2007118691-A1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203582-A1 | LYSOBACTIN AMIDES | AADAT, HAMP, DLST | CASP1 2095/4885CASP3 2701/4885CASP4 1676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.