Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TYMP | P19971 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27538958 | 0.83 | LMNA (0.52) | LMNAKMT2A | |
| SCHEMBL22440027 | 0.82 | MAPK1 (0.39) | MAPK1TK1HPGDTYMP | |
| SCHEMBL2635616 | 0.81 | MAPK1 (0.42) | MAPK1TK1HPGDTYMP | |
| SCHEMBL16914966 | 0.81 | MAPK1 (0.38) | MAPK1TK1HPGDTYMP | |
| SCHEMBL8910349 | 0.80 | MAPK1 (0.41) | MAPK1TK1HPGDTYMP | |
| SCHEMBL28402505 | 0.76 | TK1 (0.39) | MAPK1TK1HPGDTYMP | |
| SCHEMBL8412383 | 0.75 | TYMP (0.43) | MAPK1TK1HPGDTYMP | |
| SCHEMBL24052575 | 0.74 | TK1 (0.55) | MAPK1TK1HPGD | |
| SCHEMBL16915037 | 0.73 | TYMP (0.41) | MAPK1TK1TYMPKMT2A | |
| SCHEMBL28236112 | 0.72 | CRBN (0.43) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012149604-A1 | BIS-THYMINE DERIVATIVES AND PHOTO-REVERSIBLE POLYMERS THEREOF | MONASH UNIVERSITY (AU) | 2012-11-08 | — | — | WO | disclosed |