Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.43 |
| ▸ | TK1 | P04183 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16915037 | 0.82 | TYMP (0.41) | TYMPTK1MAPK1 | |
| SCHEMBL8910349 | 0.81 | MAPK1 (0.41) | TYMPTK1MAPK1HPGD | |
| SCHEMBL2635616 | 0.79 | MAPK1 (0.42) | TYMPTK1MAPK1HPGD | |
| SCHEMBL13724687 | 0.75 | MAPK1 (0.43) | TYMPTK1MAPK1HPGD | |
| SCHEMBL20587576 | 0.74 | CRBN (0.41) | — | |
| SCHEMBL24052575 | 0.72 | TK1 (0.55) | TK1MAPK1HPGD | |
| SCHEMBL22440027 | 0.71 | MAPK1 (0.39) | TYMPTK1MAPK1HPGD | |
| SCHEMBL27831324 | 0.70 | LMNA (0.45) | HPGD | |
| SCHEMBL16914966 | 0.70 | MAPK1 (0.38) | TYMPTK1MAPK1HPGD | |
| SCHEMBL3025206 | 0.70 | MAPK1 (0.46) | TYMPTK1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454651-B1 | Novel platelet-aggregation inhibitors | MONSANTO CO (US) | 1999-07-28 | — | — | EP | disclosed |
| US-5091396-A | Guanidinoalkanoylaspartylpyridine derivatives; anticoagulants | MONSANTO CO. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0454651-A2 | Novel platelet-aggregation inhibitors | MONSANTO COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-5037808-A | Indolyl platelet-aggregation inhibitors | MONSANTO CO. (US) | 1991-08-06 | — | — | US | disclosed |