Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 4/20 | 0.40 |
| ▸ | TK1 | P04183 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2635616 | 0.84 | MAPK1 (0.42) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL8412383 | 0.81 | TYMP (0.43) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL13724687 | 0.80 | MAPK1 (0.43) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL24052575 | 0.76 | TK1 (0.55) | MAPK1HPGDTK1 | |
| SCHEMBL22440027 | 0.75 | MAPK1 (0.39) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL16915037 | 0.75 | TYMP (0.41) | MAPK1TYMPTK1 | |
| SCHEMBL3025206 | 0.74 | MAPK1 (0.46) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL16914966 | 0.74 | MAPK1 (0.38) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL6703360 | 0.73 | MAPK1 (0.45) | MAPK1HPGDTYMPTK1 | |
| SCHEMBL4342113 | 0.72 | TYMP (0.49) | MAPK1HPGDTYMPTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677439-A | PREVENTION GENE EXPRESSION | SANOFI (FR) | 1997-10-14 | — | — | US | disclosed |
| EP-0541722-B1 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION | STERLING WINTHROP INC (US) | 1995-12-20 | — | — | EP | disclosed |
| EP-0541722-A1 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION. | STERLING WINTHROP INC (US) | 1993-05-19 | — | — | EP | disclosed |
| WO-1992002534-A2 | COMPOUNDS AND METHODS FOR INHIBITING GENE EXPRESSION | STERLING DRUG, INC. (US) | 1992-02-20 | — | — | WO | disclosed |