SCHEMBL2635616

SCHEMBL2635616

CC(=O)On1cc(C)c(=O)[nH]c1=O

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.42
▸ HPGD P15428 1/20 0.41
▸ TYMP P19971 4/20 0.40
▸ TK1 P04183 2/20 0.40
▸ ALDH1A1 P00352 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8910349 0.84 MAPK1 (0.41) MAPK1HPGDTYMPTK1
SCHEMBL13724687 0.81 MAPK1 (0.43) MAPK1HPGDTYMPTK1
SCHEMBL27744847 0.81 LMNA (0.46) —
SCHEMBL28402505 0.80 TK1 (0.39) MAPK1HPGDTYMPTK1
SCHEMBL28483586 0.79 LMNA (0.44) —
SCHEMBL8412383 0.79 TYMP (0.43) MAPK1HPGDTYMPTK1
SCHEMBL29100437 0.78 KMT2A (0.36) —
SCHEMBL24052575 0.78 TK1 (0.55) MAPK1HPGDTK1
SCHEMBL22440027 0.77 MAPK1 (0.39) MAPK1HPGDTYMPTK1
SCHEMBL16914966 0.76 MAPK1 (0.38) MAPK1HPGDTYMPTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039583-B Side-chain base biodegradable polyester amide with stereocomplex crystallization performance and enzymatic preparation method thereof 浙江农林大学 2025-03-11 — — CN claimed
CN-119039583-A Side-chain base biodegradable polyester amide with stereocomplex crystallization performance and enzymatic preparation method thereof 浙江农林大学 2024-11-29 — — CN claimed
CN-114053248-B Nucleic acid and small molecule drug co-delivery nano-preparation for regulating tumor metabolism and preparation method thereof 复旦大学 2023-10-20 — — CN claimed
EP-1062383-A4 ELECTROLYTE AND TIN-SILVER ELECTROPLATING PROCESS LEARONAL INC (US) 2002-08-14 — — EP claimed
US-6210556-B1 FOR DEPOSITING TIN-RICH TIN-SILVER ALLOYS UPON A SUBSTRATE LEARONAL, INC. 2001-04-03 — — US claimed
EP-1062383-A1 ELECTROLYTE AND TIN-SILVER ELECTROPLATING PROCESS LeaRonal, Inc. (US) 2000-12-27 — — EP claimed
WO-1999041433-A1 ELECTROLYTE AND TIN-SILVER ELECTROPLATING PROCESS LEARONAL, INC. (US) 1999-08-19 — — WO claimed
CN-119039583-B Side-chain base biodegradable polyester amide with stereocomplex crystallization performance and enzymatic preparation method thereof 浙江农林大学 2025-03-11 — — CN disclosed
CN-119039583-A Side-chain base biodegradable polyester amide with stereocomplex crystallization performance and enzymatic preparation method thereof 浙江农林大学 2024-11-29 — — CN disclosed
CN-118221661-A Squaric acid amide fluorescent probe based on thiophenyl quinoline for identifying adenosine triphosphate and preparation method thereof 常州大学 2024-06-21 — — CN disclosed
CN-118146198-A Squaraine fluorescent probe based on methimazole and preparation method and application thereof 常州大学 2024-06-07 — — CN disclosed
CN-114053248-B Nucleic acid and small molecule drug co-delivery nano-preparation for regulating tumor metabolism and preparation method thereof 复旦大学 2023-10-20 — — CN disclosed
US-10093674-B2 Supramolecular nanofibers and hydrogels based on nucleic acids functionalized with nucleobases BRANDEIS UNIVERSITY (US) 2018-10-09 — — US disclosed
US-5714606-A OLIGONUCLEOTIDE HAVING RECEPTOR BINDING SITES; ENZYME INHIBITORS, ANTIINFLAMMATORY AGENTS, MEDICAL DIAGNOSIS ISIS PHARMACEUTICALS, INC. (US) 1998-02-03 — — US disclosed
EP-0789707-A1 AMINO ACID NUCLEIC ACIDS ICN PHARMACEUTICALS (US) 1997-08-20 — — EP disclosed
EP-0739335-A4 PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS ISIS PHARMACEUTICALS INC (US) 1997-04-02 — — EP disclosed
EP-0739335-A1 PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS ISIS PHARMACEUTICALS, INC. (US) 1996-10-30 — — EP disclosed
WO-1996020212-A2 PEPTIDE NUCLEIC ACID INCORPORATING A CHIRAL BACKBONE BUCHARDT, DORTE (DK) 1996-07-04 — — WO disclosed
WO-1996014330-A1 AMINO ACID NUCLEIC ACIDS ICNPHARMACEUTICALS (US) 1996-05-17 — — WO disclosed
WO-1995018792-A1 PYRROLIDINE-CONTAINING MONOMERS AND OLIGOMERS ISIS PHARMACEUTICALS, INC. (US) 1995-07-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10093674-B2 Supramolecular nanofibers and hydrogels based on nucleic acids functionalized with nucleobases PHAX, PCNA, RBM28 MAPK1 3319/4885HPGD 3354/4885TYMP 619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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