Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORD | Q00796 | 5/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | JMJD1C | Q15652 | 1/20 | 0.35 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 8/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13728021 | 0.84 | KDM4E (0.39) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL3947074 | 0.81 | ALDH1A1 (0.40) | TSHRKDM4EKDM5ALMNA | |
| SCHEMBL13728173 | 0.80 | OPRM1 (0.40) | KDM4EGRM2 | |
| SCHEMBL6647003 | 0.80 | NR3C2 (0.48) | KDM5A | |
| SCHEMBL3264151 | 0.80 | DGAT1 (0.39) | TSHRKDM4ELMNA | |
| SCHEMBL13412503 | 0.80 | OPRM1 (0.34) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL2826624 | 0.80 | ADORA3 (0.37) | ADORA3TSHRMC4RADRA1AMC3R | |
| SCHEMBL13727788 | 0.79 | MEN1 (0.39) | LMNA | |
| SCHEMBL13729797 | 0.77 | PARP10 (0.49) | TSHRKDM4EGRM2LMNA | |
| SCHEMBL10695791 | 0.76 | ADORA3 (0.34) | ADORA3TSHRMC4RADRA1AMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |