Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 7/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6305112 | 0.84 | NNMT (0.39) | OPRM1IKBKBNNMTSIRT6GRM2 | |
| SCHEMBL13728021 | 0.82 | KDM4E (0.39) | OPRM1IKBKBALDH1A1HPGDHCRTR1 | |
| SCHEMBL13729797 | 0.81 | PARP10 (0.49) | ALDH1A1HPGDGRM2KDM4E | |
| SCHEMBL13729259 | 0.80 | SORD (0.40) | GRM2KDM4E | |
| SCHEMBL3947074 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4E | |
| SCHEMBL2826624 | 0.78 | ADORA3 (0.37) | OPRM1ALDH1A1HPGDNNMTSIRT6 | |
| SCHEMBL3264151 | 0.78 | DGAT1 (0.39) | ALDH1A1KDM4EHCAR2 | |
| SCHEMBL13412503 | 0.78 | OPRM1 (0.34) | OPRM1NNMTSIRT6GRM2HCRTR1 | |
| SCHEMBL13727788 | 0.77 | MEN1 (0.39) | HCAR2 | |
| SCHEMBL6647003 | 0.75 | NR3C2 (0.48) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012151567-A1 | PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2012-11-08 | — | — | WO | disclosed |