Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729610 | 0.78 | KIF11 (0.52) | LMNATHRBKIF11ADORA3CHUK | |
| SCHEMBL10367290 | 0.76 | ALOX5 (0.44) | LMNAADORA3MAPTKDM4EMEN1 | |
| SCHEMBL5249070 | 0.73 | TRPV3 (0.43) | LMNATHRBKIF11ADORA3CHUK | |
| SCHEMBL30862210 | 0.73 | KIF11 (0.58) | LMNATHRBKIF11ADORA3CHUK | |
| SCHEMBL28827814 | 0.72 | LMNA (0.56) | LMNATHRBKIF11ADORA3KDM4E | |
| SCHEMBL22497605 | 0.72 | KIF11 (0.48) | LMNATHRBKIF11ADORA3CHUK | |
| SCHEMBL29414652 | 0.72 | KIF11 (0.48) | LMNATHRBKIF11ADORA3CHUK | |
| SCHEMBL17269505 | 0.71 | KIF11 (0.62) | LMNATHRBKIF11ADORA3CHUK | |
| SCHEMBL8031410 | 0.71 | LMNA (0.62) | KCNH2LMNATHRBKIF11ADORA3 | |
| SCHEMBL9013368 | 0.71 | ADORA3 (0.47) | LMNATHRBKIF11ADORA3CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9566284-B2 | Agents and methods for treating ischemic and other diseases | NONO INC. (CA) | 2017-02-14 | — | — | US | disclosed |
| US-9566284-B2 | Agents and methods for treating ischemic and other diseases | NONO INC. (CA) | 2017-02-14 | — | — | US | disclosed |