SCHEMBL1373404

SCHEMBL1373404

C=CS(=O)(=O)c1ccc([N]CC)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.48
NPC1 O15118 1/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
XBP1 P17861 1/20 0.48
MAPK1 P28482 1/20 0.48
HTT P42858 1/20 0.48
RAB9A P51151 1/20 0.48
MDM2 Q00987 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TLR9 Q9NR96 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
CTSK P43235 1/20 0.32
POLB P06746 1/20 0.32
CYP2D6 P10635 1/20 0.32
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1373952 0.80 NOS1 (0.37) MAPTNPC1ALDH1A1LMNATP53
SCHEMBL2447623 0.79 CYP2D6 (0.52) MAPTNPC1ALDH1A1LMNATSHR
SCHEMBL10860893 0.77 ALDH1A1 (0.73) MAPTNPC1ALDH1A1LMNATP53
SCHEMBL18034190 0.76 MAPT (0.50) MAPTNPC1ALDH1A1LMNATP53
SCHEMBL7034572 0.75 CA2 (0.55) MAPTNPC1ALDH1A1LMNATP53
SCHEMBL8914438 0.75 NPC1 (0.53) MAPTNPC1ALDH1A1LMNATP53
SCHEMBL21881986 0.74 SMN1; SMN2 (0.41) MAPTNPC1ALDH1A1LMNATP53
SCHEMBL10180637 0.72 CA2 (0.58) MAPTNPC1ALDH1A1LMNATP53
SCHEMBL10538581 0.72 MAPK1 (0.50) MAPTNPC1ALDH1A1LMNATP53
SCHEMBL19844938 0.71 MAPT (0.46) MAPTNPC1ALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1934293-B2 AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2020-12-09 EP disclosed
EP-2391683-B1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DISTRIB GMBH (DE) 2017-03-29 EP disclosed
CN-102292400-B The disazo dyes of fibre-active copper complexing DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2016-01-20 CN disclosed
US-9062208-B2 Fiber-reactive copper complex disazo dyes DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2015-06-23 US disclosed
EP-1490441-B2 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DYSTAR COLOURS DISTRIB GMBH (DE) 2012-12-26 EP disclosed
EP-1934293-B1 AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2012-07-18 EP disclosed
CN-102292400-A Fiber-reactive copper complex disazo dyes 2011-12-21 CN disclosed
US-8080101-B2 Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-12-20 US disclosed
US-20110283465-A1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-11-24 US disclosed
EP-1789499-B1 DYE MIXTURES OF FIBRE-REACTIVE AZO DYES PRODUCTION AND USE THEREOF DYSTAR COLOURS DEUTSCHLAND (DE) 2011-03-23 EP disclosed
EP-1508598-A1 Mixture of fiberreactive azo dyes process for their preparation and use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2005-02-23 EP disclosed
EP-1508596-A1 Mixtures of azo reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2005-02-23 EP disclosed
US-20050034252-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO. (DE) 2005-02-17 US disclosed
US-20050034253-A1 Mixture; ink for ink jet printing DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-02-17 US disclosed
EP-1499681-A1 FIBRE-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2005-01-26 EP disclosed
EP-1490441-A1 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2004-12-29 EP disclosed
EP-1490442-A1 DYE MIXTURES OF FIBRE REACTIVE AZODYES, PRODUCTION AND USE THEREOF DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2004-12-29 EP disclosed
WO-2003089521-A1 FIBRE-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-10-30 WO disclosed
WO-2003080741-A1 DYE MIXTURES OF FIBRE REACTIVE AZODYES, PRODUCTION AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-10-02 WO disclosed
WO-2003080739-A1 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-10-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050034252-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and their use CRY1, FZD7, CBR3 MAPT 3415/4885NPC1 4770/4885ALDH1A1 617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.