Sugi Predict

Sugi Predict / Compounds / SCHEMBL1373952

SCHEMBL1373952

SCHEMBL1373952

C=CS(=O)(=O)c1cccc([N]CC)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOS1 P29475 1/20 0.37
▸ CA2 P00918 9/20 0.36
▸ CA9 Q16790 9/20 0.36
▸ CA7 P43166 4/20 0.36
▸ CA1 P00915 4/20 0.36
▸ ALDH1A1 P00352 3/20 0.36
▸ TSHR P16473 2/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ NPC1 O15118 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ TP53 P04637 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ XBP1 P17861 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ RAB9A P51151 1/20 0.36
▸ MDM2 Q00987 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ BTK Q06187 1/20 0.34
▸ CA12 O43570 5/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6240592 0.81 TSHR (0.47) NOS1CA2CA9CA7CA1
SCHEMBL1373404 0.80 MAPT (0.48) NOS1CA2CA9CA7CA1
SCHEMBL54845 0.76 TSHR (0.50) CA2CA9CA1ALDH1A1TSHR
SCHEMBL10181530 0.75 LOXL2 (0.43) CA2ALDH1A1TSHRSMN1; SMN2NPC1
SCHEMBL1373956 0.74 CA1 (0.42) CA2CA9CA1ALDH1A1TSHR
SCHEMBL10180546 0.72 KAT6A (0.44) CA2ALDH1A1TSHRSMN1; SMN2NPC1
SCHEMBL13214022 0.72 KMT2A (0.50) ALDH1A1TSHRSMN1; SMN2NPC1LMNA
SCHEMBL14573196 0.71 TP53 (0.46) CA2CA9CA7CA1ALDH1A1
SCHEMBL7029934 0.71 ALDH1A1 (0.46) ALDH1A1TSHRSMN1; SMN2NPC1LMNA
SCHEMBL10181228 0.71 HDAC4 (0.47) CA2CA9CA1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1934293-B2 AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2020-12-09 — — EP disclosed
EP-2391683-B1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DISTRIB GMBH (DE) 2017-03-29 — — EP disclosed
CN-102292400-B The disazo dyes of fibre-active copper complexing DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2016-01-20 — — CN disclosed
US-9062208-B2 Fiber-reactive copper complex disazo dyes DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2015-06-23 — — US disclosed
EP-1490441-B2 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DYSTAR COLOURS DISTRIB GMBH (DE) 2012-12-26 — — EP disclosed
EP-1934293-B1 AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2012-07-18 — — EP disclosed
CN-102292400-A Fiber-reactive copper complex disazo dyes — 2011-12-21 — — CN disclosed
US-8080101-B2 Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-12-20 — — US disclosed
US-20110283465-A1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DEUTSCHLAND GMBH (DE) 2011-11-24 — — US disclosed
EP-1789499-B1 DYE MIXTURES OF FIBRE-REACTIVE AZO DYES PRODUCTION AND USE THEREOF DYSTAR COLOURS DEUTSCHLAND (DE) 2011-03-23 — — EP disclosed
EP-1508596-A1 Mixtures of azo reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2005-02-23 — — EP disclosed
EP-1508598-A1 Mixture of fiberreactive azo dyes process for their preparation and use DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2005-02-23 — — EP disclosed
US-20050034252-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO. (DE) 2005-02-17 — — US disclosed
US-20050034253-A1 Mixture; ink for ink jet printing DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-02-17 — — US disclosed
EP-1499681-A1 FIBRE-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2005-01-26 — — EP disclosed
EP-1490442-A1 DYE MIXTURES OF FIBRE REACTIVE AZODYES, PRODUCTION AND USE THEREOF DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2004-12-29 — — EP disclosed
EP-1490441-A1 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 2004-12-29 — — EP disclosed
WO-2003089521-A1 FIBRE-REACTIVE AZO DYES, THEIR PRODUCTION AND THEIR USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-10-30 — — WO disclosed
WO-2003080741-A1 DYE MIXTURES OF FIBRE REACTIVE AZODYES, PRODUCTION AND USE THEREOF DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-10-02 — — WO disclosed
WO-2003080739-A1 DYE MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PRODUCTION AND USE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2003-10-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050034252-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and their use CRY1, FZD7, CBR3 NOS1 81/4885CA2 615/4885CA9 399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.