Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21082799 | 1.00 | ALDH1A1 (0.48) | ALDH1A1ACE2GPR84FFAR1MAPT | |
| SCHEMBL13733268 | 1.00 | ALDH1A1 (0.48) | ALDH1A1ACE2GPR84FFAR1MAPT | |
| SCHEMBL6234057 | 0.93 | CA2 (0.47) | ALDH1A1ACE2GPR84FFAR1MAPT | |
| SCHEMBL19569931 | 0.84 | ACE2 (0.44) | ALDH1A1ACE2GPR84FFAR1MAPT | |
| SCHEMBL3304320 | 0.83 | GPR84 (0.55) | ALDH1A1ACE2GPR84FFAR1MAPT | |
| SCHEMBL3902890 | 0.83 | GPR84 (0.55) | ALDH1A1ACE2GPR84FFAR1MAPT | |
| SCHEMBL3299361 | 0.83 | GPR84 (0.55) | ALDH1A1ACE2GPR84FFAR1MAPT | |
| SCHEMBL3913154 | 0.83 | GPR84 (0.55) | ALDH1A1ACE2GPR84FFAR1MAPT | |
| SCHEMBL2488736 | 0.83 | GPR84 (0.55) | ALDH1A1ACE2GPR84FFAR1MAPT | |
| SCHEMBL5027014 | 0.83 | GPR84 (0.55) | ALDH1A1ACE2GPR84FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240335364-A1 | COMPOSITIONS OF DICAFFEOYLQUINIC ACIDS WITH TOCOPHEROL | SYMRISE AG (DE) | 2024-10-10 | — | — | US | disclosed |
| EP-4442241-A2 | RETINOL REPLACEMENT IN SKIN TREATMENT | Symrise AG (DE) | 2024-10-09 | — | — | EP | disclosed |
| EP-3773445-B1 | RETINOL REPLACEMENT IN SKIN TREATMENT | SYMRISE AG (DE) | 2024-07-24 | — | — | EP | disclosed |
| EP-4373462-A1 | COMPOSITIONS OF DICAFFEOYLQUINIC ACIDS WITH TOCOPHEROL | Symrise AG (DE) | 2024-05-29 | — | — | EP | disclosed |
| US-11801210-B2 | Retinol replacement in skin treatment | SYMRISE AG (DE) | 2023-10-31 | — | — | US | disclosed |
| WO-2023001385-A1 | COMPOSITIONS OF DICAFFEOYLQUINIC ACIDS WITH TOCOPHEROL | SYMRISE AG (DE) | 2023-01-26 | — | — | WO | disclosed |
| US-20210045983-A1 | RETINOL REPLACEMENT IN SKIN TREATMENT | SYMRISE AG (DE) | 2021-02-18 | — | — | US | disclosed |
| EP-3773445-A1 | RETINOL REPLACEMENT IN SKIN TREATMENT | Symrise AG (DE) | 2021-02-17 | — | — | EP | disclosed |
| CN-111918637-A | Retinol substitute in skin treatment | 西姆莱斯有限公司 | 2020-11-10 | — | — | CN | disclosed |
| WO-2019185923-A1 | RETINOL REPLACEMENT IN SKIN TREATMENT | SYMRISE AG (DE) | 2019-10-03 | — | — | WO | disclosed |
| US-20160008297-A1 | COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) | B.R.A.I.N. BIOTECHNOLOGY RESEARCH AND INFORMATION NETWORK AG (DE) | 2016-01-14 | — | — | US | disclosed |
| EP-2887929-A2 | COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) | Symrise AG (DE) | 2015-07-01 | — | — | EP | disclosed |
| WO-2012143576-A2 | COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) | SYMRISE AG (DE) | 2012-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210045983-A1 | RETINOL REPLACEMENT IN SKIN TREATMENT | RBP1, RBP4, LRAT | ALDH1A1 23/4885ACE2 3921/4885GPR84 512/4885 |
| US-11801210-B2 | Retinol replacement in skin treatment | RBP1, RBP4, LRAT | ALDH1A1 22/4885ACE2 3768/4885GPR84 451/4885 |
| US-20160008297-A1 | COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) | TRPV2, TRPV1, TRPM2 | ALDH1A1 2905/4885ACE2 272/4885GPR84 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.