SCHEMBL13736330

SCHEMBL13736330

Nc1cc(O)nn1-c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.61
CYP2C19 P33261 2/20 0.61
MAPK1 P28482 1/20 0.61
SMN1; SMN2 Q16637 9/20 0.54
RAB9A P51151 9/20 0.54
ALDH1A1 P00352 4/20 0.54
KMT2A Q03164 3/20 0.54
MEN1 O00255 2/20 0.54
TSHR P16473 1/20 0.54
GFER P55789 1/20 0.54
NPC1 O15118 7/20 0.51
MAPT P10636 2/20 0.51
PKM P14618 2/20 0.51
KDM4E B2RXH2 2/20 0.51
STAT1 P42224 1/20 0.51
LMNA P02545 1/20 0.51
TP53 P04637 1/20 0.51
PTGS1 P23219 1/20 0.50
NFKB1 P19838 2/20 0.49
NFKB2 Q00653 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19388861 0.84 RAB9A (0.43) CYP1A2CYP2C19MAPK1SMN1; SMN2RAB9A
SCHEMBL10715419 0.81 MAPK1 (0.42) CYP1A2CYP2C19MAPK1SMN1; SMN2RAB9A
SCHEMBL18692224 0.81 MEN1 (0.54) CYP1A2CYP2C19MAPK1SMN1; SMN2RAB9A
SCHEMBL20386597 0.81 NPC1 (0.53) CYP1A2CYP2C19MAPK1SMN1; SMN2RAB9A
SCHEMBL18593711 0.81 RAB9A (0.62) CYP1A2CYP2C19MAPK1SMN1; SMN2RAB9A
SCHEMBL19732026 0.80 PTGS1 (0.57) CYP1A2CYP2C19MAPK1SMN1; SMN2RAB9A
SCHEMBL7837159 0.79 CYP1A2 (0.66) CYP1A2CYP2C19MAPK1SMN1; SMN2RAB9A
SCHEMBL14554235 0.77 LMNA (0.69) SMN1; SMN2RAB9AALDH1A1KMT2AMEN1
SCHEMBL20386582 0.77 SMN1; SMN2 (0.41) CYP1A2CYP2C19MAPK1SMN1; SMN2RAB9A
SCHEMBL19750006 0.77 NPY5R (0.44) CYP1A2CYP2C19MAPK1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12180187-B2 1-phenyl-5-azinylpyrazolyl-3-oxyalkyl acids and their use for controlling unwanted plant growth BAYER AKTIENGESELLSCHAFT (DE) 2024-12-31 US disclosed
CN-114071999-B 1-Phenyl-5-azinylpyrazolyl-3-oxyalkyl acids and their use for controlling unwanted plant growth 拜耳公司 2024-08-27 CN disclosed
US-20230066946-A1 1,5-DIPHENYLPYRAZOLYL-3-OXYALKYL ACIDS AND 1-PHENYL-5-THIENYLPYRAZOLYL-3-OXYALKYL ACIDS AND THE USE THEREOF FOR CONTROL OF UNWANTED PLANT GROWTH BAYER AKTIENGESELLSCHAFT (DE) 2023-03-02 US disclosed
EP-4075979-A1 1,5-DIPHENYLPYRAZOLYL-3-OXYALKYL ACIDS AND 1-PHENYL-5-THIENYLPYRAZOLYL-3-OXYALKYL ACIDS AND THE USE THEREOF FOR CONTROL OF UNDESIRED PLANT GROWTH Bayer Aktiengesellschaft (DE) 2022-10-26 EP disclosed
CN-115135152-A 1, 5-diphenylpyrazolyl-3-oxyalkyl acids and 1-phenyl-5-thienylpyrazolyl-3-oxyalkyl acids and their use for controlling undesired vegetation 拜耳公司 2022-09-30 CN disclosed
US-20220235036-A1 1-PHENYL-5-AZINYLPYRAZOLYL-3-OXYALKYL ACIDS AND THEIR USE FOR CONTROLLING UNWANTED PLANT GROWTH BAYER AKTIENGESELLSCHAFT (DE) 2022-07-28 US disclosed
EP-3975720-A1 1-PHENYL-5-AZINYL PYRAZOLYL-3-OXYALKYL ACIDS AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH Bayer Aktiengesellschaft (DE) 2022-04-06 EP disclosed
CN-114071999-A 1-phenyl-5-azinylpyrazolyl-3-oxyalkyl acids and their use for controlling undesired vegetation 拜耳公司 2022-02-18 CN disclosed
WO-2021122728-A1 1,5-DIPHENYLPYRAZOLYL-3-OXYALKYL ACIDS AND 1-PHENYL-5-THIENYLPYRAZOLYL-3-OXYALKYL ACIDS AND THE USE THEREOF FOR CONTROL OF UNDESIRED PLANT GROWTH BAYER AKTIENGESELLSCHAFT (DE) 2021-06-24 WO disclosed
WO-2020245044-A1 1-PHENYL-5-AZINYL PYRAZOLYL-3-OXYALKYL ACIDS AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH BAYER AKTIENGESELLSCHAFT (DE) 2020-12-10 WO disclosed
US-10358445-B2 Respiratory formulations and compounds for use therein Respivert, Ltd. (GB) 2019-07-23 US disclosed
US-20180201611-A1 Respiratory formulations and compounds for use therein RESPIVERT LTD. (GB) 2018-07-19 US disclosed
WO-2012149157-A2 HETEROCYCLIC COMPOUNDS FOR THE INHIBITION OF PASK BIOENERGENIX (US) 2012-11-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10358445-B2 Respiratory formulations and compounds for use therein TSLP, CCL11, RORB CYP1A2 117/4885CYP2C19 304/4885MAPK1 2007/4885
US-12180187-B2 1-phenyl-5-azinylpyrazolyl-3-oxyalkyl acids and their use for controlling unwanted plant growth AGPS, CYP51A1, PGLS CYP1A2 208/4885CYP2C19 1555/4885MAPK1 777/4885
US-20230066946-A1 1,5-DIPHENYLPYRAZOLYL-3-OXYALKYL ACIDS AND 1-PHENYL-5-THIENYLPYRAZOLYL-3-OXYALKYL ACIDS AND THE USE THEREOF FOR CONTROL OF UNWANTED PLANT GROWTH NOTUM, AGPS, DDT CYP1A2 291/4885CYP2C19 638/4885MAPK1 1888/4885
US-20220235036-A1 1-PHENYL-5-AZINYLPYRAZOLYL-3-OXYALKYL ACIDS AND THEIR USE FOR CONTROLLING UNWANTED PLANT GROWTH AGPS, CYP51A1, PGLS CYP1A2 208/4885CYP2C19 1555/4885MAPK1 777/4885
US-20180201611-A1 Respiratory formulations and compounds for use therein TSLP, CCL11, RORB CYP1A2 117/4885CYP2C19 304/4885MAPK1 2007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.