SCHEMBL1374040

SCHEMBL1374040

COc1[c]cc(OC)[c]c1

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9511309 0.84
SCHEMBL160506 0.72
SCHEMBL105204 0.72 CA1 (0.48) ALDH1A1KDM4EMAPK1CA12CA1
SCHEMBL1178329 0.72
SCHEMBL28053489 0.70 CA1 (0.46) ALDH1A1KDM4EMAPK1CA12CA1
SCHEMBL21590 0.70
SCHEMBL158430 0.70 HTR2A (0.30)
SCHEMBL27488332 0.70 CA1 (0.46) ALDH1A1KDM4EMAPK1CA12CA1
SCHEMBL19917 0.70
SCHEMBL1870100 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443861-B2 Organic electroluminescence device SUMITOMO CHEMICAL CO (JP) 2008-05-28 EP claimed
US-7183418-B2 Mono-, oligo- and polythieno[2,3-b]thiophenes MERCK PATENT GESELLSCHAFT (DE) 2007-02-27 US claimed
EP-1182501-B1 Photographic processing composition containing bistriazinyl arylenediamine derivative FUJI PHOTO FILM CO LTD (JP) 2006-07-26 EP claimed
CN-1227567-C Photographic composition containing ditriazinyl sub-aryl diamine derivatives FUJITSU LTD (JP) 2005-11-16 CN claimed
US-20050090640-A1 Mono-, oligo-and polythieno[2,3-b]thiophenes FLEXENABLE TECHNOLOGY LIMITED (GB) 2005-04-28 US claimed
EP-1510535-A1 Mono-, Oligo- and Polythieno(2,3-b)thiophenes MERCK PATENT GmbH (DE) 2005-03-02 EP claimed
US-20050034252-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR TEXTILFARBEN GMBH & CO. (DE) 2005-02-17 US claimed
US-20050034253-A1 Mixture; ink for ink jet printing DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2005-02-17 US claimed
US-6753425-B2 BIS(2,6-DIAMINOTRIAZIN-4- YL)ARYLENEDIAMINE DERIVATIVE HAVING SULFONIC ACID, CARBOXYLIC, AND/OR HYDROXYL GROUP; SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIALS; DISCOLORATION INHIBITION; ANTISOILANTS FUJI PHOTO FILM CO., LTD. (JP) 2004-06-22 US claimed
US-20040009439-A1 Photographic processing composition containing bistriazinyl arylenediamine derivative FUJI PHOTO FILM CO., LTD. 2004-01-15 US claimed
EP-0443861-A2 Organic electroluminescence device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-08-28 EP claimed
US-4988608-A Method for forming fine pattern of conjugated polymer film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-01-29 US claimed
US-4868284-A SULFONIUM CONTAINING PRECURSOR POLYMER DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1989-09-19 US claimed
US-4791177-A STRETCH-ORIENTED SULFONIUM POLYELECTROLYTE; HIGH STRENGTH AND MODULUS DIRECTOR-GENERAL OF THE AGENCY OF SCIENCE AND TECHNOLOGY, AN ORGAN OF THE MINISTRY OF INTERNATIONAL TRADE AND INDUSTRY OF JAPAN (JP) 1988-12-13 US claimed
US-4626588-A BIAXIALLY STRETCHING SULFONIUM POLYELECTROLYTE FILM, ANNEALING; ELECTROCONDUCTIVE DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1986-12-02 US claimed
US-4599193-A Highly electroconductive pyrolyzed product retaining its original shape and composition formed therefrom DIRECTOR-GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY, AN ORGAN OF THE MINISTRY OF INTERNATIONAL TRADE AND INDUSTRY OF JAPAN (JP) 1986-07-08 US claimed
US-4567048-A SULFONATED INDOXYL DERIVATIVES PFIZER INC. (US) 1986-01-28 US claimed
US-4528118-A Highly electroconductive conjugated polymer composition and process for producing the same AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1985-07-09 US claimed
US-4285863-A YELLOW-TO-RED ORGANIC PIGMENTS; PLASTICS AND FABRICS; PAINTS, ENAMELS, AND INKS MONTEDISON S.P.A. (IT) 1981-08-25 US claimed
US-4048148-A Polyazomethine fibers and films E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-09-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050034252-A1 Dye mixtures of fiber-reactive azo dyes, their preparation and their use CRY1, FZD7, CBR3 ALDH1A1 617/4885KDM4E 1778/4885MAPK1 2241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.