Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR0B1 | P51843 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MGAT2 | Q10469 | 3/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.33 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.33 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.33 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241046 | 0.84 | DEGS1 (0.42) | NR0B1ROCK2ROCK1KDR | |
| SCHEMBL13744417 | 0.78 | POLB (0.43) | NR0B1MEN1ALDH1A1KMT2APOLB | |
| SCHEMBL13743845 | 0.78 | MEN1 (0.47) | NR0B1MEN1ALDH1A1KMT2APOLB | |
| SCHEMBL13743228 | 0.77 | HDAC1 (0.50) | KDRMEN1ALDH1A1KMT2APOLB | |
| SCHEMBL13743377 | 0.77 | HPGDS (0.39) | KDRMMP2MMP9MMP8MEN1 | |
| SCHEMBL13744231 | 0.76 | MGLL (0.44) | ROCK2MEN1ALDH1A1KMT2APOLB | |
| SCHEMBL13744096 | 0.76 | NPC1 (0.38) | NR0B1MMP1MMP2MMP3MMP9 | |
| SCHEMBL13752778 | 0.76 | ROCK2 (0.38) | NR0B1ROCK2ALDH1A1 | |
| SCHEMBL13743921 | 0.76 | DEGS1 (0.46) | KDRALDH1A1 | |
| SCHEMBL13744095 | 0.76 | RAB9A (0.40) | MMP1MMP2MMP3MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | HURLEY TIMOTHY BRIAN | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203694-A1 | INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE | FDPS, UMPS, GGPS1 | NR0B1 2001/4885ROCK2 4337/4885ROCK1 4029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.