Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 14/20 | 0.57 |
| ▸ | NPC1 | O15118 | 12/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8289620 | 0.75 | RAB9A (0.67) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL3403591 | 0.72 | NPC1 (1.00) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL7674903 | 0.72 | GAA (0.61) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL30100826 | 0.71 | RAB9A (0.64) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL28921534 | 0.71 | RAB9A (0.64) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL7004914 | 0.71 | NPC1 (0.61) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL8401808 | 0.70 | TP53 (0.70) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL8289583 | 0.69 | HPGD (0.74) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL12414424 | 0.69 | RAB9A (0.59) | RAB9ANPC1KDM4EMEN1KMT2A | |
| SCHEMBL18015404 | 0.69 | MEN1 (0.55) | RAB9ANPC1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009100438-A2 | COMPOUNDS THAT ENHANCE ATOH-1 EXPRESSION | MASSACHUSETTS EYE & EAR INFIRMARY (US) | 2009-08-13 | — | — | WO | disclosed |