Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25178201 | 0.79 | ESR1 (0.46) | TDP1CYP3A4HIF1APTGS2PTGS1 | |
| SCHEMBL804146 | 0.79 | DPP4 (0.54) | ALDH1A1MAPK1HIF1ALMNACYP2D6 | |
| SCHEMBL5862033 | 0.79 | DPP4 (0.54) | ALDH1A1MAPK1HIF1ALMNACYP2D6 | |
| SCHEMBL4674647 | 0.79 | DPP4 (0.54) | ALDH1A1MAPK1HIF1ALMNACYP2D6 | |
| SCHEMBL804233 | 0.79 | DPP4 (0.54) | ALDH1A1MAPK1HIF1ALMNACYP2D6 | |
| SCHEMBL3886489 | 0.79 | DPP4 (0.54) | ALDH1A1MAPK1HIF1ALMNACYP2D6 | |
| SCHEMBL16967371 | 0.79 | DPP4 (0.54) | ALDH1A1MAPK1HIF1ALMNACYP2D6 | |
| SCHEMBL7415779 | 0.79 | DPP4 (0.54) | ALDH1A1MAPK1HIF1ALMNACYP2D6 | |
| SCHEMBL16967416 | 0.78 | ADRB2 (0.52) | HSD17B10TSHRCYP3A4CYP2C9LMNA | |
| SCHEMBL831692 | 0.78 | ADRB2 (0.52) | HSD17B10TSHRCYP3A4CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090198084-A1 | PROCESS FOR THE DEPROTECTION OF PROTECTED AMINES | DSM IP ASSETS B.V. (NL) | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090198084-A1 | PROCESS FOR THE DEPROTECTION OF PROTECTED AMINES | BCAT2, ADH1C, BCAT1 | HSD17B10 839/4885ALDH1A1 96/4885TSHR 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.