Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716391 | 0.91 | ALDH1A1 (0.62) | ALDH1A1MAPK1MEN1KMT2ASRD5A2 | |
| SCHEMBL13595551 | 0.91 | TSHR (0.61) | ALDH1A1MAPK1HPGDPKMNPC1 | |
| SCHEMBL30871744 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MAPK1MEN1KMT2ASRD5A2 | |
| SCHEMBL12876370 | 0.88 | RAB9A (0.58) | ALDH1A1MAPK1KMT2AHPGDNPC1 | |
| SCHEMBL20944622 | 0.88 | MEN1 (0.59) | ALDH1A1MAPK1MEN1KMT2ASRD5A2 | |
| SCHEMBL5744650 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MAPK1MEN1KMT2ASRD5A2 | |
| SCHEMBL13595550 | 0.88 | RAB9A (0.55) | ALDH1A1MAPK1MEN1KMT2AHPGD | |
| SCHEMBL29463151 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MAPK1MEN1KMT2ASRD5A2 | |
| Methylone SCHEMBL25263013 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPK1MEN1KMT2ASRD5A2 | |
| Methylone SCHEMBL1826389 | 0.85 | ALDH1A1 (0.56) | ALDH1A1MAPK1MEN1KMT2ASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567417-B | Preparation and application of benzamide compounds | 山东绿霸化工股份有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-117567417-A | Preparation and application of benzamide compounds | 山东绿霸化工股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
| US-20230192642-A1 | ISOTOPOLOGUES SALTS, CRYSTALLINE FORMS, STEREOISOMERS, OF METHYLONE AND ETHYLONE AND METHODS OF USE THEREOF | TERRAN BIOSCIENCES INC. | 2023-06-22 | — | — | US | disclosed |
| CN-113788856-B | Oxime ester thiophosphoryl amine compound and preparation method and application thereof | 青岛农业大学 | 2023-02-21 | — | — | CN | disclosed |
| US-20220411426-A1 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-12-29 | — | — | US | disclosed |
| CN-113788856-A | Oxime ester thiophosphoryl amine compound and preparation method and application thereof | 青岛农业大学 | 2021-12-14 | — | — | CN | disclosed |
| US-11040976-B2 | Substrate selective inhibitors of insulin-degrading enzyme (IDE) and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-06-22 | — | — | US | disclosed |
| US-20190016723-A9 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-01-17 | — | — | US | disclosed |
| US-7919523-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-7919523-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS, INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20100093747-A1 | METHOD OF INDUCING NEGATIVE CHEMOTAXIS | CELTAXSYS, INC. | 2010-04-15 | — | — | US | disclosed |
| WO-2009111447-A2 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2009-09-11 | — | — | WO | disclosed |
| US-20090220662-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. | 2009-09-03 | — | — | US | disclosed |
| US-20090042973-A1 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED | 2009-02-12 | — | — | US | disclosed |
| US-20090042973-A1 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED | 2009-02-12 | — | — | US | disclosed |
| US-7442718-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-10-28 | — | — | US | disclosed |
| US-7442718-B2 | Inhibitors of aspartyl protease | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2008-10-28 | — | — | US | disclosed |
| US-4116665-A | Method of regulating the growth of aquatic weeds with pyridine derivatives | ELI LILLY AND COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093747-A1 | METHOD OF INDUCING NEGATIVE CHEMOTAXIS | PMAIP1, CDC42, DCX | ALDH1A1 3761/4885MAPK1 2519/4885MEN1 4129/4885 |
| US-20090042973-A1 | Inhibitors of aspartyl protease | SPINT2, DNPEP, PRSS1 | ALDH1A1 1604/4885MAPK1 3466/4885MEN1 4418/4885 |
| US-20090220662-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | TAS2R10, TAS2R41, TAS2R30 | ALDH1A1 408/4885MAPK1 3252/4885MEN1 4307/4885 |
| US-20230192642-A1 | ISOTOPOLOGUES SALTS, CRYSTALLINE FORMS, STEREOISOMERS, OF METHYLONE AND ETHYLONE AND METHODS OF USE THEREOF | PYGB, NR3C2, CYP11B1 | ALDH1A1 2288/4885MAPK1 2072/4885MEN1 1408/4885 |
| US-20220411426-A1 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | IDE, SI, GPR119 | ALDH1A1 1111/4885MAPK1 2982/4885MEN1 3889/4885 |
| US-20190016723-A9 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | IDE, SI, GPR119 | ALDH1A1 1194/4885MAPK1 3017/4885MEN1 3885/4885 |
| US-11040976-B2 | Substrate selective inhibitors of insulin-degrading enzyme (IDE) and uses thereof | IDE, SI, GPR119 | ALDH1A1 1194/4885MAPK1 3017/4885MEN1 3885/4885 |
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | ALDH1A1 1863/4885MAPK1 4249/4885MEN1 4306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.