SCHEMBL13775191

SCHEMBL13775191

Cc1ccc2c(c1)c(N(c1cc(C)c(C)c(C)c1)c1cc(C)c(C)c(C)c1)cc1c3ccc(C)cc3c(N(c3cc(C)c(C)c(C)c3)c3cc(C)c(C)c(C)c3)cc21

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.32
CYP2A6 P11509 1/20 0.32
KDM1A O60341 2/20 0.32
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
LDHA P00338 1/20 0.30
LDHB P07195 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13775276 0.95 CYP1A2 (0.33) CYP1A2CYP2A6KDM1AKDM4EALDH1A1
SCHEMBL13775194 0.94 KIF11 (0.34) CYP1A2CYP2A6KDM1A
SCHEMBL13775275 0.92 KIF11 (0.35) CYP1A2CYP2A6KDM1AGAA
SCHEMBL14492751 0.89 KDM1A (0.33) KDM1ALMNA
SCHEMBL13775214 0.87 KDM1A (0.32) KDM1A
SCHEMBL13775183 0.84 ALDH1A1 (0.33) CYP1A2CYP2A6KDM1AKDM4EALDH1A1
SCHEMBL13775208 0.83
SCHEMBL2536348 0.81 CYP1A2 (0.34) CYP1A2CYP2A6ALDH1A1LMNAGAA
SCHEMBL13775204 0.81 KDM1A (0.31) CYP1A2KDM1A
SCHEMBL13775190 0.80 LMNA (0.37) KDM1AKDM4ELMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090189522-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDERNITSU KOSAN CO., LTD. (JP) 2009-07-30 US disclosed
US-7524568-B2 Aromatic amine derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2009-04-28 US disclosed
US-7524568-B2 Aromatic amine derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2009-04-28 US disclosed
US-20080268283-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-10-30 US disclosed
US-20080268283-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-10-30 US disclosed
US-7425653-B2 Aromatic amine derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2008-09-16 US disclosed
US-7425653-B2 Aromatic amine derivative and organic electroluminescence device employing the same IDEMITSU KOSAN CO., LTD. (JP) 2008-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080268283-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME TYR, MAOA, AOC2 CYP1A2 345/4885CYP2A6 2415/4885KDM1A 159/4885
US-20090189522-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME TYR, MAOA, AOC2 CYP1A2 345/4885CYP2A6 2415/4885KDM1A 159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.