SCHEMBL2536348

SCHEMBL2536348

Cc1cc(N(c2cc(C)c(C)c(C)c2)c2cc3c4ccccc4c(N(c4cc(C)c(C)c(C)c4)c4cc(C)c(C)c(C)c4)cc3c3ccccc23)cc(C)c1C

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.34
ACHE P22303 1/20 0.33
CYP2A6 P11509 4/20 0.32
TSHR P16473 1/20 0.32
GAA P10253 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13775204 0.95 KDM1A (0.31) CYP1A2ACHE
SCHEMBL2538872 0.93 CYP1A2 (0.35) CYP1A2CYP2A6
SCHEMBL13775275 0.92 KIF11 (0.35) CYP1A2CYP2A6GAAHTT
SCHEMBL2544680 0.92 CYP1A2 (0.33) CYP1A2CYP2A6TSHR
SCHEMBL13775194 0.90 KIF11 (0.34) CYP1A2CYP2A6HTT
SCHEMBL13775212 0.89 KDM1A (0.32) CYP1A2CYP2A6TSHR
SCHEMBL13775209 0.89 KDM1A (0.32) CYP1A2CYP2A6TSHR
SCHEMBL12120980 0.89 ACHE (0.33) ACHEALDH1A1
SCHEMBL12120971 0.87 KIF11 (0.30)
SCHEMBL2536353 0.87 KIF11 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10950803-B2 Compounds and uses in devices UNIVERSAL DISPLAY CORPORATION (US) 2021-03-16 US disclosed
US-20190319194-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed
US-10381569-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
US-20160149139-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-26 US disclosed
US-20160149139-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2016-05-26 US disclosed
US-20160104847-A1 NOVEL COMPOUNDS AND USES IN DEVICES UNIVERSAL DISPLAY CORPORATION 2016-04-14 US disclosed
US-20160104847-A1 NOVEL COMPOUNDS AND USES IN DEVICES UNIVERSAL DISPLAY CORPORATION 2016-04-14 US disclosed
US-8058478-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-11-15 US disclosed
US-8058478-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-11-15 US disclosed
US-8044390-B2 Material for organic electroluminescent device, organic electroluminescent device, and organic electroluminescent display IDEMITSU KOSAN CO., LTD. (JP) 2011-10-25 US disclosed
US-20110034733-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2011-02-10 US disclosed
US-20110034733-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2011-02-10 US disclosed
US-7816017-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2010-10-19 US disclosed
US-7816017-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2010-10-19 US disclosed
US-20100181555-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENT DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY IDEMITSU KOSAN CO., LTD. (JP) 2010-07-22 US disclosed
EP-1860096-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE UTILIZING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2007-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110034733-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, DDC, EML4 CYP1A2 1093/4885ACHE 153/4885CYP2A6 2958/4885
US-20100181555-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENT DEVICE, AND ORGANIC ELECTROLUMINESCENT DISPLAY AFF4, CLIC4, L1CAM CYP1A2 1454/4885ACHE 1587/4885CYP2A6 4584/4885
US-20160104847-A1 NOVEL COMPOUNDS AND USES IN DEVICES TERT, UACA, TXN CYP1A2 3435/4885ACHE 1324/4885CYP2A6 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.