Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13780980 | 0.82 | TDP1 (0.47) | MEN1KMT2ASRD5A2TDP1L3MBTL1 | |
| SCHEMBL13781015 | 0.80 | LMNA (0.47) | MEN1KMT2ASRD5A2TDP1L3MBTL1 | |
| SCHEMBL27828940 | 0.79 | L3MBTL1 (0.61) | MEN1KMT2ASMN1; SMN2SRD5A2TDP1 | |
| SCHEMBL13780986 | 0.79 | L3MBTL1 (0.53) | MEN1KMT2ASRD5A2TDP1L3MBTL1 | |
| SCHEMBL13780985 | 0.78 | L3MBTL1 (0.43) | MEN1KMT2ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL3916584 | 0.78 | RAB9A (0.49) | SIRT1MEN1KMT2ASMN1; SMN2SRD5A2 | |
| SCHEMBL14163856 | 0.78 | CYP2D6 (0.44) | MEN1KMT2ASMN1; SMN2KCNK9HDAC8 | |
| SCHEMBL13781089 | 0.78 | L3MBTL1 (0.65) | MEN1KMT2ASMN1; SMN2SRD5A2TDP1 | |
| SCHEMBL17284937 | 0.77 | SRD5A2 (0.56) | SIRT1MEN1KMT2ASMN1; SMN2SRD5A2 | |
| SCHEMBL26662921 | 0.77 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206351-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-9206351-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, OR10J3, PUF60 | SIRT1 3429/4885MEN1 405/4885KMT2A 3329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.