Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13781015 | 0.98 | LMNA (0.47) | TDP1ATML3MBTL1LMNAALDH1A1 | |
| SCHEMBL13780986 | 0.97 | L3MBTL1 (0.53) | TDP1ATML3MBTL1LMNAALDH1A1 | |
| SCHEMBL28654162 | 0.86 | POLB (0.49) | TDP1ATML3MBTL1HPGDCNR2 | |
| SCHEMBL13780988 | 0.85 | ATM (0.38) | TDP1ATML3MBTL1LMNAALDH1A1 | |
| SCHEMBL27828940 | 0.83 | L3MBTL1 (0.61) | TDP1ATML3MBTL1LMNAALDH1A1 | |
| SCHEMBL22175357 | 0.83 | ALDH1A1 (0.45) | TDP1ATML3MBTL1LMNAALDH1A1 | |
| SCHEMBL12551413 | 0.83 | ALDH1A1 (0.45) | TDP1ATML3MBTL1LMNAALDH1A1 | |
| SCHEMBL13780979 | 0.82 | SIRT1 (0.47) | TDP1ATML3MBTL1ALDH1A1NPC1 | |
| SCHEMBL13780985 | 0.82 | L3MBTL1 (0.43) | TDP1ATML3MBTL1LMNAALDH1A1 | |
| SCHEMBL13781089 | 0.82 | L3MBTL1 (0.65) | TDP1ATML3MBTL1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206351-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-9206351-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-12-08 | — | — | US | disclosed |
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090167166-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, OR10J3, PUF60 | TDP1 1282/4885ATM 3136/4885L3MBTL1 3570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.