Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13788727 | 0.84 | CARM1 (0.41) | LMNAKMT2A | |
| SCHEMBL6882141 | 0.84 | POLB (0.37) | CYP1A2KMT2AKDM1APOLBHTR2C | |
| SCHEMBL11641093 | 0.81 | CDC7 (0.40) | LMNAKMT2AMLNRNR1I2CHRM2 | |
| SCHEMBL13788693 | 0.80 | SLC6A2 (0.35) | LMNACYP2D6CYP1A2KMT2AKDM4E | |
| SCHEMBL8529944 | 0.79 | LMNA (0.31) | LMNAHTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL11805576 | 0.77 | KDM1A (0.34) | KDM1APOLBADRA2AADRA2BADRA2C | |
| SCHEMBL11645508 | 0.71 | UTS2R (0.34) | LMNAMLNRNR1I2CHRM2ADRB1 | |
| SCHEMBL13849307 | 0.71 | KDM1A (0.33) | KDM1AHTR2ABRD4 | |
| SCHEMBL11730098 | 0.71 | ALOX12 (0.33) | LMNACYP2D6KMT2AKDM4EPKM | |
| SCHEMBL8524367 | 0.69 | KDM1A (0.33) | KDM4EKDM1AOPRM1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1750704-B1 | UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2009-07-22 | — | — | EP | disclosed |