SCHEMBL8524367

SCHEMBL8524367

C=CCC1(CC=C)CNc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.33
BRD4 O60885 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRL1 P41146 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7673834 0.83 KDM1A (0.45) KDM1A
SCHEMBL6882141 0.76 POLB (0.37) KDM1ABRD4ALDH1A1OPRM1OPRL1
SCHEMBL7103198 0.75 KDM4E (0.31) KDM4EALDH1A1
SCHEMBL11805576 0.73 KDM1A (0.34) KDM1ABRD4ALDH1A1OPRM1OPRL1
SCHEMBL4906291 0.72 SIGMAR1 (0.35) ALDH1A1
SCHEMBL13788693 0.70 SLC6A2 (0.35) KDM1ABRD4KDM4EOPRM1
SCHEMBL28969992 0.69 PGR (0.37) KDM4EALDH1A1
SCHEMBL13788728 0.69 LMNA (0.36) KDM1ABRD4KDM4EOPRM1
SCHEMBL5502981 0.69 KDM1A (0.33) KDM1A
SCHEMBL13849307 0.67 KDM1A (0.33) KDM1ABRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5968725-A MATERIAL COMPRISING ON SUPPORT SILVER HALIDE PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, REDUCING AGENT, ULTRAHIGH CONTRAST PROMOTING AGENT, SELECTED HETEROCYCLIC MERCAPTO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1999-10-19 US disclosed
US-5236807-A Negative, hydrazine compound FUJI PHOTO FILM CO., LTD. (JP) 1993-08-17 US disclosed
US-4769316-A Method for restraining the formation of re-reversal negative image in direct positive silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-09-06 US disclosed
US-4607006-A Silver halide photographic light-sensitive material containing non-spectral sensitizing electron donative silver halide adsorptive compound FUJI PHOTO FILM CO., LTD. (JP) 1986-08-19 US disclosed
WO-1983002610-A1 DERIVATIVES OF 3,3-DIALKYL-INDOLIN AND OF 3,3-ALKYLENE-INDOLIN, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM SANDOZ AG (CH) 1983-08-04 WO disclosed
US-4028353-A CYANINE DYES, PHOTOGRAPHY POLAROID CORPORATION (US) 1977-06-07 US disclosed
US-3976493-A CYANINE DYES POLAROID CORPORATION (US) 1976-08-24 US disclosed