Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR1E | P28566 | 1/20 | 0.30 |
| ▸ | HTR1F | P30939 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13788728 | 0.79 | LMNA (0.36) | LMNAHTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL13788693 | 0.66 | SLC6A2 (0.35) | LMNAHTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL11805576 | 0.66 | KDM1A (0.34) | HTR5A | |
| SCHEMBL6882141 | 0.66 | POLB (0.37) | HTR2CHTR5A | |
| SCHEMBL11641093 | 0.65 | CDC7 (0.40) | LMNAHTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL27866953 | 0.65 | HTR7 (0.42) | LMNAHTR7HTR5A | |
| SCHEMBL11645508 | 0.64 | UTS2R (0.34) | LMNAHTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL11730098 | 0.61 | ALOX12 (0.33) | LMNAHTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL11643574 | 0.61 | DRD2 (0.39) | HTR1AHTR2AHTR2CHTR2BHTR3A | |
| SCHEMBL13849307 | 0.61 | KDM1A (0.33) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639072-B1 | PHARMACEUTICAL COMPOSITIONS OF ALKYLSULPHONAMIDES 5HT1 AGONISTS FOR RECTAL ADMINISTRATION | GLAXO WELLCOME LAB (FR) | 1998-03-11 | — | — | EP | disclosed |
| EP-0639072-A1 | PHARMACEUTICAL COMPOSITIONS OF ALKYLSULPHONAMIDES 5HT1 AGONISTS FOR RECTAL ADMINISTRATION | LABORATOIRE GLAXO WELLCOME (FR) | 1995-02-22 | — | — | EP | disclosed |
| WO-1993021916-A1 | PHARMACEUTICAL COMPOSITIONS OF ALKYLSULPHONAMIDES 5HT1 AGONISTS FOR RECTAL ADMINISTRATION | LABORATOIRES GLAXO SA (FR) | 1993-11-11 | — | — | WO | disclosed |