Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8189543 | 0.84 | KIF11 (0.60) | KIF11MEN1KMT2AAPOBEC3GMAPT | |
| SCHEMBL22100414 | 0.76 | KDM4E (0.50) | KIF11MEN1KMT2AAPOBEC3GKDM4E | |
| SCHEMBL6072669 | 0.75 | KIF11 (0.59) | KIF11MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL12286224 | 0.74 | KIF11 (0.66) | KIF11MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29760781 | 0.74 | PTGS2 (0.70) | KIF11MEN1KMT2AMAPTGABRA1 | |
| SCHEMBL498758 | 0.74 | PTGS2 (0.70) | KIF11MEN1KMT2AMAPTGABRA1 | |
| SCHEMBL11467664 | 0.73 | SLC6A3 (0.50) | KMT2A | |
| SCHEMBL11298149 | 0.73 | KIF11 (0.60) | KIF11MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL24213214 | 0.72 | KMT2A (0.46) | KIF11MEN1KMT2AAPOBEC3GKDM4E | |
| SCHEMBL10892550 | 0.72 | KIF11 (1.00) | KIF11KDM4EALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4705630-B2 | — | — | 2011-06-22 | — | — | JP | claimed |