Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281248 | 0.90 | RAB9A (0.55) | KMT2ASMN1; SMN2RAB9ALMNAGALR3 | |
| SCHEMBL13806436 | 0.85 | KMT2A (0.58) | KMT2ASMN1; SMN2RAB9ALMNAGALR3 | |
| SCHEMBL13806437 | 0.82 | LMNA (0.58) | KMT2ASMN1; SMN2RAB9ALMNAGALR3 | |
| SCHEMBL9302673 | 0.78 | MAPK14 (0.75) | KMT2ASMN1; SMN2LMNAMAPK14MEN1 | |
| SCHEMBL4288438 | 0.77 | EPHX2 (0.56) | KMT2ASMN1; SMN2RAB9ALMNAGALR3 | |
| SCHEMBL4281554 | 0.74 | KMT2A (0.54) | KMT2ASMN1; SMN2RAB9ALMNAGALR3 | |
| SCHEMBL178366 | 0.72 | MAPK14 (0.75) | KMT2ASMN1; SMN2RAB9ALMNAMAPK14 | |
| SCHEMBL20445356 | 0.71 | LMNA (0.56) | KMT2ASMN1; SMN2RAB9ALMNANAMPT | |
| SCHEMBL1767434 | 0.71 | HDAC1 (0.60) | KMT2ASMN1; SMN2RAB9ALMNAMAPK14 | |
| SCHEMBL29520232 | 0.70 | LMNA (1.00) | KMT2ASMN1; SMN2RAB9ALMNAGALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156582-A1 | Pyrazole Compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156582-A1 | Pyrazole Compound | GSK3B, GSK3A, GSKIP | KMT2A 871/4885SMN1; SMN2 4064/4885RAB9A 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.