Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TTR | P02766 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 4/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GMNN | O75496 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13849463 | 0.87 | ALDH1A1 (0.62) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL20914998 | 0.80 | AKR1B10 (0.72) | ALDH1A1TTRKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL30449068 | 0.80 | AKR1B10 (0.72) | ALDH1A1TTRKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28989637 | 0.80 | APP (0.66) | ALDH1A1TTRKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7908387 | 0.78 | ALDH1A1 (0.65) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7908382 | 0.78 | ALDH1A1 (0.65) | ACHEALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4624106 | 0.78 | APP (0.67) | SMN1; SMN2APPAKR1B10AKR1B1EGFR | |
| SCHEMBL4624105 | 0.78 | APP (0.67) | SMN1; SMN2APPAKR1B10AKR1B1EGFR | |
| SCHEMBL29040562 | 0.77 | AKR1B10 (0.71) | ALDH1A1TTRKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL4866988 | 0.77 | TTR (0.64) | TTRAPPCYP3A4MAPTEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009076618-A2 | GENERATION OF COMBINATORIAL SYNTHETIC LIBRARIES AND SCREENING FOR NOVEL PROADHESINS AND NONADHESINS | CERNOFINA, LLC (US) | 2009-06-18 | — | — | WO | disclosed |
| US-20090124690-A1 | Generation of Combinatorial Synthetic Libraries and Screening for Novel Proadhesins and Nonadhesins | CERNOFINA, LLC | 2009-05-14 | — | — | US | disclosed |
| US-20090016990-A1 | Antimicrobial Compositions | CUTLER, ELIOT | 2009-01-15 | — | — | US | disclosed |
| WO-2008092006-A2 | ANTIMICROBIAL COMPOSITIONS | CERNOFINA, LLC (US) | 2008-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090124690-A1 | Generation of Combinatorial Synthetic Libraries and Screening for Novel Proadhesins and Nonadhesins | SELP, SELE, SELPLG | ACHE 4274/4885ALDH1A1 1723/4885TTR 1985/4885 |
| US-20090016990-A1 | Antimicrobial Compositions | C5, TLR1, PRF1 | ACHE 3787/4885ALDH1A1 791/4885TTR 3846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.