Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.33 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA7 | P43166 | 2/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21214242 | 0.81 | MEN1 (0.43) | HTR5AGRIA1CACNG8AHRKMT2A | |
| SCHEMBL6285150 | 0.76 | HTR5A (0.41) | HTR5AGRIA1CACNG8DAOKMT2A | |
| SCHEMBL9670200 | 0.76 | CASP6 (0.51) | GRIA1CACNG8DAOKMT2AALDH1A1 | |
| SCHEMBL27418874 | 0.74 | HTR5A (0.53) | HTR5ADAOKMT2ACREBBPALDH1A1 | |
| SCHEMBL11537645 | 0.74 | NPC1 (0.47) | HTR5AGRIA1CACNG8DAOAHR | |
| SCHEMBL688899 | 0.72 | GRIA1 (0.42) | GRIA1CACNG8AHRCACNG2KMT2A | |
| SCHEMBL433799 | 0.72 | AHR (0.61) | HTR5AGRIA1CACNG8DAOAHR | |
| SCHEMBL20991136 | 0.72 | HTR5A (0.47) | HTR5AGRIA1CACNG8DAOAHR | |
| SCHEMBL19142696 | 0.72 | HTR5A (0.47) | HTR5AGRIA1CACNG8DAOAHR | |
| SCHEMBL12330258 | 0.70 | HTR5A (0.40) | HTR5AGRIA1CACNG8DAOCREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541462-B2 | Triaminophosphine ligands for carbon-nitrogen and carbon-carbon bond formation | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-20080139806-A1 | TRIAMINOPHOSPHINE LIGANDS FOR CARBON-NITROGEN AND CARBON-CARBON BOND FORMATION | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.. | 2008-06-12 | — | — | US | disclosed |
| US-7385058-B1 | Triaminophosphine ligands for carbon-nitrogen and carbon-carbon bond formation | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2008-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139806-A1 | TRIAMINOPHOSPHINE LIGANDS FOR CARBON-NITROGEN AND CARBON-CARBON BOND FORMATION | ABL1, AOC1, NPPA | HTR5A 3777/4885GRIA1 1044/4885CACNG8 4484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.