Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SNCA | P37840 | 2/20 | 0.48 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812667 | 0.84 | PTGS1 (0.56) | PTGS1TDP1CDK1THRBTHRA | |
| SCHEMBL13812600 | 0.84 | LTA4H (0.61) | PTGS1TDP1CDK1THRBTHRA | |
| SCHEMBL13812636 | 0.82 | THRB (0.59) | PTGS1TDP1CDK1THRBTHRA | |
| SCHEMBL6357721 | 0.78 | ALDH1A1 (0.66) | TDP1ALDH1A1L3MBTL1GAAHTT | |
| SCHEMBL3859317 | 0.76 | TUBB (0.65) | TDP1THRBTHRAALDH1A1L3MBTL1 | |
| SCHEMBL13812638 | 0.76 | NPC1 (0.54) | PTGS1TDP1CDK1THRBTHRA | |
| SCHEMBL6361572 | 0.75 | ALDH1A1 (0.66) | TDP1THRBALDH1A1L3MBTL1GAA | |
| SCHEMBL13812693 | 0.75 | THRB (0.53) | PTGS1TDP1CDK1THRBTHRA | |
| SCHEMBL13812615 | 0.74 | TUBB (0.59) | THRBTHRAALDH1A1L3MBTL1GAA | |
| SCHEMBL11471586 | 0.74 | FFAR1 (0.60) | ALDH1A1L3MBTL1GAAHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-7547804-B2 | Compounds, compositions, and methods employing same | MYRIAD GENETICS, INC. (US) | 2009-06-16 | — | — | US | disclosed |