Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.37 |
| ▸ | PRSS12 | P56730 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13813864 | 0.88 | HPGD (0.36) | SCN9AALOX15FFAR2ALDH1A1NPSR1 | |
| SCHEMBL3159128 | 0.65 | SCN9A (0.59) | SCN9A | |
| SCHEMBL10401308 | 0.65 | SMN1; SMN2 (0.57) | ALDH1A1 | |
| SCHEMBL21578016 | 0.61 | KDM4E (0.60) | ALOX15FFAR2ALDH1A1 | |
| SCHEMBL5027028 | 0.61 | KEAP1 (0.55) | ALDH1A1NPSR1TDP1 | |
| SCHEMBL30646082 | 0.60 | CA9 (0.55) | ALDH1A1TDP1 | |
| SCHEMBL19695306 | 0.60 | ALDH1A1 (0.49) | ALDH1A1 | |
| SCHEMBL4849617 | 0.60 | XDH (0.50) | — | |
| SCHEMBL16086080 | 0.60 | ALOX15 (0.54) | ALOX15FFAR2 | |
| SCHEMBL31030191 | 0.60 | ALDH1A1 (0.51) | ALDH1A1NPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130072471-A1 | Inhibitors of Ion Channels | MARRON BRIAN EDWARD (US) | 2013-03-21 | — | — | US | disclosed |
| US-8357711-B2 | Heterocyclic sulfonamides as inhibitors of ion channels | PFIZER LIMITED (GB) | 2013-01-22 | — | — | US | disclosed |
| US-20090143358-A1 | INHIBITORS OF ION CHANNELS | ICAGEN, INC. (US) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072471-A1 | Inhibitors of Ion Channels | TRPV1, TRPV5, TRPA1 | SCN9A 51/4885PRSS12 470/4885ALOX15 1107/4885 |
| US-20090143358-A1 | INHIBITORS OF ION CHANNELS | TRPV1, TRPV5, TRPA1 | SCN9A 51/4885PRSS12 470/4885ALOX15 1107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.