Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Ethacridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CASP7 | P55210 | 3/20 | 1.00 |
| ▸ | CASP1 | P29466 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 0.80 |
| ▸ | TERT | O14746 | 1/20 | 0.80 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | THRB | P10828 | 1/20 | 0.80 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethacridine SCHEMBL30775016 | 1.00 | MEN1 (1.00) | MEN1KMT2ACASP7CASP1KDM4E | |
| Ethacridine SCHEMBL30006678 | 1.00 | MEN1 (1.00) | MEN1KMT2ACASP7CASP1KDM4E | |
| Ethacridine SCHEMBL31197660 | 1.00 | MEN1 (1.00) | MEN1KMT2ACASP7CASP1KDM4E | |
| Ethacridine SCHEMBL8676831 | 0.99 | MEN1 (0.98) | MEN1KMT2ACASP7CASP1KDM4E | |
| Ethacridine SCHEMBL1649444 | 0.99 | MEN1 (0.98) | MEN1KMT2ACASP7CASP1KDM4E | |
| Ethacridine SCHEMBL29568982 | 0.99 | MEN1 (0.98) | MEN1KMT2ACASP7CASP1KDM4E | |
| Ethacridine SCHEMBL29355684 | 0.99 | MEN1 (0.98) | MEN1KMT2ACASP7CASP1KDM4E | |
| Ethacridine SCHEMBL3967085 | 0.98 | MEN1 (0.96) | MEN1KMT2ACASP7CASP1KDM4E | |
| Lactic Acid SCHEMBL8375854 | 0.95 | MEN1 (0.91) | MEN1KMT2ACASP7CASP1KDM4E | |
| Ethacridine SCHEMBL193949 | 0.89 | MEN1 (1.00) | MEN1KMT2ACASP7CASP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1623 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144911-A1 | BURN WOUND TREATMENT | Marie's Original Formulas LLC (US) | 2026-05-28 | — | — | US | claimed |
| US-20260144910-A1 | BURN WOUND TREATMENT | Marie's Original Formulas LLC (US) | 2026-05-28 | — | — | US | claimed |
| EP-4640238-A1 | THERAPEUTIC AGENT FOR PULMONARY DISEASE, HEPATIC DISEASE OR RENAL DISEASE, WHICH CONTAINS PGAM-CHK1 BINDING INHIBITOR | Kyoto University (JP) | 2025-10-29 | — | — | EP | claimed |
| US-20250213551-A1 | WOUND TREATMENT | Marie's Original Formulas LLC | 2025-07-03 | — | — | US | claimed |
| US-20250186651-A1 | HYDROGEL-BASED TOPICAL WOUND DRESSING CONTAINING PROTEIN EXTRACT | T&R BIOFAB CO., LTD. (KR) | 2025-06-12 | — | — | US | claimed |
| US-12311074-B1 | Burn wound treatment | Marie's Original Formulas LLC (US) | 2025-05-27 | — | — | US | claimed |
| US-12274830-B2 | Nitric oxide inhalation therapy for infants with bronchiolitis | BEYOND AIR LTD (IL) | 2025-04-15 | — | — | US | claimed |
| US-12247246-B2 | Identification of inhibitors of TcpC and TIR NADase activity | WASHINGTON UNIVERSITY (US) | 2025-03-11 | — | — | US | claimed |
| CN-119280450-A | Medical fabric dressing with long-acting disinfection and sterilization functions and preparation method thereof | 孙国明 | 2025-01-10 | — | — | CN | claimed |
| US-20250003952-A1 | SENOLYTIC DRUG SCREENING METHOD AND SENOLYTIC DRUG | KYOTO UNIVERSITY (JP) | 2025-01-02 | — | — | US | claimed |
| EP-0071647-B1 | PROCESS FOR RECOVERING INTERFERON | GREEN CROSS CORPORATION (JP) | 1984-12-05 | — | — | EP | claimed |
| US-4455146-A | THERMOPLASTIC ELASTOMERS, OILS OR FATTY ACID, TACKFIER, AND A MEDICINE | HISAMITSU PHARMACEUTICAL CO., LTD. (JP) | 1984-06-19 | — | — | US | claimed |
| EP-0097440-A1 | Method and kit for removing and assaying complement system fragments | THE UPJOHN COMPANY (US) | 1984-01-04 | — | — | EP | claimed |
| EP-0071647-A1 | PROCESS FOR RECOVERING INTERFERON | GREEN CROSS CORPORATION (JP) | 1983-02-16 | — | — | EP | claimed |
| US-4137222-A | GLOBULINS, PLASMIN, FROM HUMAN BLOOD | INSTITUT MERIEUX (FR) | 1979-01-30 | — | — | US | claimed |
| US-4129648-A | BLOOD PLASMA OR SERUM EXTRACT | COLLIER HARRY O J | 1978-12-12 | — | — | US | claimed |
| US-4104125-A | Process for producing human lysozyme | THE GREEN CROSS CORPORATION (JP) | 1978-08-01 | — | — | US | claimed |
| US-4017470-A | Method for preparing a heat-stable plasma protein solution from paste IV-1 | THE GREEN CROSS CORPORATION (JA) | 1977-04-12 | — | — | US | claimed |
| US-3972858-A | SILICIC ACID, ELUTION | BEHRINGWERKE AKTIENGESELLSCHAFT | 1976-08-03 | — | — | US | claimed |
| US-3946105-A | CHROMATOGRAPHY, DIALYSIS, IMMUNIZATION, BLEEDING, ABSORPTION | KOWA COMPANY, LTD. (JA) | 1976-03-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12247246-B2 | Identification of inhibitors of TcpC and TIR NADase activity | NADK, NAPRT, TIPARP | MEN1 3678/4885KMT2A 3095/4885CASP7 4463/4885 |
| US-20260144910-A1 | BURN WOUND TREATMENT | CUTA, COL1A1, MMP1 | MEN1 4599/4885KMT2A 4768/4885CASP7 1204/4885 |
| US-20260144911-A1 | BURN WOUND TREATMENT | CUTA, LIPG, COL1A1 | MEN1 4650/4885KMT2A 4740/4885CASP7 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.