Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TACR3 | P29371 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13967978 | 0.82 | SCN9A (0.56) | ADORA2ASCN9ADHODHMAPK10MEN1 | |
| SCHEMBL13836819 | 0.81 | KMT2A (0.49) | SCN9ANPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL13837207 | 0.78 | ADORA2A (0.45) | ADORA2ASCN9APIK3R1PIK3CATACR3 | |
| SCHEMBL13837047 | 0.76 | CFTR (0.46) | NPC1ALDH1A1RAB9AMAPTAHR | |
| SCHEMBL17363620 | 0.76 | MBNL1 (0.61) | MBNL1ADORA2APIK3R1PIK3CANPC1 | |
| SCHEMBL13836924 | 0.73 | MEN1 (0.62) | ADORA2APIK3R1PIK3CAALDH1A1RAB9A | |
| SCHEMBL13967979 | 0.71 | RAB9A (0.47) | NPC1ALDH1A1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL3672070 | 0.70 | ALDH1A1 (0.44) | SCN9ANPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL5810725 | 0.70 | ALDH1A1 (0.44) | SCN9ANPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL27993150 | 0.68 | MBNL1 (0.62) | MBNL1ADORA2APIK3R1PIK3CANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952192-B2 | Phosphorylated and branched dihydroxy-pentane-dione (DPD) analogs as quorum sensing inhibitors in bacteria | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2015-02-10 | — | — | US | disclosed |
| US-20120294900-A1 | Phosphorylated and Branched Dihydroxy-Pentane-Dione (DPD) Analogs as Quorum Sensing Inhibitors in Bacteria | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120294900-A1 | Phosphorylated and Branched Dihydroxy-Pentane-Dione (DPD) Analogs as Quorum Sensing Inhibitors in Bacteria | PGD, DUSP2, PGLS | MBNL1 1621/4885ADORA2A 383/4885SCN9A 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.